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Chyluria and delayed graft function in early posttransplant period in a renal transplant patient. | LitMetric

AI Article Synopsis

  • * Following the transplant, the patient had chylous urine output of 300-400 mL daily and exhibited only pretibial edema with no signs of kidney rejection or damage found during a renal biopsy.
  • * After 15 days, the chyluria resolved spontaneously, leading to the normalization of her urine output and a decrease in creatinine levels to below 1 mg/dL, marking this as the first documented case of chyluria following surgery in a post-transplant patient.

Article Abstract

Chyluria mostly occurs because of the leakage of lymphatic fluid into the urinary system from the lymphatic system. The patient reported here with end-stage renal disease caused by the nephrotic syndrome underwent renal transplantation from a living donor. During the early posttransplant period, her daily urine output was 300 to 400 mL, and it was chylous. The only abnormality on physical examination was pretibial edema. On renal biopsy, there was no sign of glomerular disease, acute tubular necrosis, or rejection that could have caused delayed graft function. All factors except surgery were excluded, and a lymphourinary fistula was demonstrated with lymphoscintigraphy. After 15 days, chyluria resolved and she recovered spontaneously. Normal diuresis began, and her creatinine level decreased to less than 1 mg/dL in 3 days. According to our knowledge, this is the first chyluria case secondary to surgery in the posttransplant setting.

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Source
http://dx.doi.org/10.1097/MAJ.0b013e3181e38d7bDOI Listing

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