Addressing the many challenges posed by escalating antimicrobial resistance requires a strategy at institutional, community, national, regional and international levels. Partners in the development of such a strategy should include representatives from clinical and veterinary medicine, public health, microbiology, animal husbandry, the pharmaceutical and agriculture industries as well as behavioral sciences. In the Middle East, antimicrobial resistance is a crisis at the present time. It stems from a wide range of problems; however, there are few studies from this region about factors associated with proliferating resistance. In this article, we explore inappropriate antimicrobial use in this part of the world and suggest possible solutions to mitigate the problem.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1586/eri.10.56 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Extracts for Cosmetic Applications: Systematic Review and Meta-Analysis.
Curr Issues Mol Biol
November 2024
Department of BioNano Technology, Gachon University, 1342 Seongnam-daero, Sujeong-gu, Seongnam-si 13120, Gyeonggi-do, Republic of Korea.
We have conducted a systematic review and meta-analysis to evaluate the cosmetic applications of extracts (DMEs). A total of 261 articles were screened; however, after eliminating inappropriate studies, only 16 individual studies were eligible. The comparative standardized mean difference (SMD) between the DME treatment and control groups was used to evaluate the cosmetic properties of DME, including its biocompatibility, whitening effects, and anti-inflammatory and antimicrobial properties.
View Article and Find Full Text PDF: Routes of Infection, Antimicrobial Resistance, and Alternative Therapies as a Means to Develop Infection Control.
Diseases
December 2024
Department of Radiology, King Fahd Armed Forces Hospital, Jeddah 23311, Saudi Arabia.
() is a Gram-negative, spiral-shaped bacterium that colonizes the gastric epithelium and is associated with a range of gastrointestinal disorders, exhibiting a global prevalence of approximately 50%. Despite the availability of treatment options, frequently reemerges and demonstrates increasing antibiotic resistance, which diminishes the efficacy of conventional therapies. Consequently, it is imperative to explore non-antibiotic treatment alternatives to mitigate the inappropriate use of antibiotics.
View Article and Find Full Text PDFPortable microfluidic devices for monitoring antibiotic resistance genes in wastewater.
Mikrochim Acta
December 2024
School of Resources, Environment and Materials, Guangxi University, Nanning, 530004, Guangxi, China.
Antibiotic resistance genes (ARGs) pose serious threats to environmental and public health, and monitoring ARGs in wastewater is a growing need because wastewater is an important source. Microfluidic devices can integrate basic functional units involved in sample assays on a small chip, through the precise control and manipulation of micro/nanofluids in micro/nanoscale spaces, demonstrating the great potential of ARGs detection in wastewater. Here, we (1) summarize the state of the art in microfluidics for recognizing ARGs, (2) determine the strengths and weaknesses of portable microfluidic chips, and (3) assess the potential of portable microfluidic chips to detect ARGs in wastewater.
View Article and Find Full Text PDFAppropriate use of vancomycin in a cardiac surgical unit.
J Cardiothorac Surg
December 2024
King Fahad Medical City, Riyad, Saudi Arabia.
Background: Antibiotic resistance is a rapidly growing problem. Methicillin-resistant staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) are major worries, particularly in developing nations where cost-effectiveness is essential. Use of vancomycin must be restricted to prevent resistant to it.
View Article and Find Full Text PDFGenetic and Genomic Approaches to the Study of Drug-Induced Liver Injury.
Liver Int
January 2025
Faculty of Medical Sciences, Translational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Idiosyncratic hepatotoxicity induced by prescribed drugs has been known since the early 20th century. Identifying risk factors, including genetic factors, that trigger this drug-induced liver injury (DILI) has been an important priority for many years, both to prevent drugs that cause liver injury being licensed and as a potential means of preventing at-risk patients being prescribed causative drugs. Improved methods for genomic analysis, particularly the development of genome-wide association studies, have facilitated the identification of genomic risk factors for DILI, but, to date, there are only two main examples, liver injury caused by amoxicillin-clavulanate (AC) and by flucloxacillin, where genetic risk factors causing the injury have been identified and replicated with understanding of the underlying mechanism.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!