Progressive macular hypomelanosis: a rarely diagnosed hypopigmentation in Caucasians.

Dermatol Res Pract

Department of Dermatology and Allergology, Ludwig-Maximilians University, Frauenlobstrasse 9-11, DE-80337 Munich, Germany.

Published: July 2011

A 35-year-old woman who developed whitish macules on trunk and limbs at 12 years of age and observed a remarkable increase of the hypopigmentated lesions after her pregnancies at ages 29 and 32 years. Because of the highly characteristic clinical aspect and the light- and electron-microscopic histopathologic findings, we diagnosed progressive macular hypomelanosis (PMH). It is a nonscaly disorder with hypopigmented macules mainly on the trunk and is more often seen in young women. In contrast to some authors assuming the presence of Propionibacterium spp. as a matter of principle in PMH, we report a case with no evidence for Propionibacterium spp.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879604PMC
http://dx.doi.org/10.1155/2009/607682DOI Listing

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