Visualizing genetic similarity at the symptom level: the example of learning disabilities.

Behav Brain Sci

MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London SE5 8AF, United Kingdom.

Published: June 2010

Psychological traits and disorders are often interrelated through shared genetic influences. A combination of maximum-likelihood structural equation modelling and multidimensional scaling enables us to open a window onto the genetic architecture at the symptom level, rather than at the level of latent genetic factors. We illustrate this approach using a study of cognitive abilities involving over 5,000 pairs of twins.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868893PMC
http://dx.doi.org/10.1017/S0140525X10000749DOI Listing

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