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Preclinical Evidence for a Drug-Drug Interaction Between Cannabinol and Melatonin.
Basic Clin Pharmacol Toxicol
January 2025
Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.
The worldwide legalization of medicinal cannabis has led to an increased use of products made by commercial operators. These products often contain minor cannabinoids such as cannabinol (CBN) which are advertised to improve sleep. Products are also available in which CBN is combined with conventional therapies, with a common product containing both CBN and the widely used sleep-aid melatonin.
View Article and Find Full Text PDFDetecting changes in tobacco product marketplace prominence using social media, advertising, sales, and web traffic data: The example of Puff Bar in the United States tobacco marketplace from 2019 to 2021.
PLoS One
December 2024
Office of Science, Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America.
Puff Bar, a disposable electronic nicotine delivery system (ENDS), was the ENDS brand most commonly used by U.S. youth in 2021.
View Article and Find Full Text PDFConsumer Understanding of Prescription Drug Indications in Direct-to-Consumer Television Advertisements.
Ther Innov Regul Sci
December 2024
RTI International, Research Triangle Park, NC, 27709, USA.
Background: Prescription drugs may be indicated to treat more than one medical condition, and companies may promote more than one indication in the same direct-to-consumer (DTC) ad. This study examined how presenting multiple prescription drug indications in one DTC television ad affects consumers' processing of drug information.
Methods: We conducted two studies with adults diagnosed with diabetes (Study 1, N = 408) or rheumatoid arthritis (Study 2, N = 411).
Efficiency and safety of cannabinoid medical use: an analysis of discussions and observed trends on Instagram.
Front Public Health
December 2024
Ludwig Boltzmann Institute Digital Health and Patient Safety, Medical University of Vienna, Vienna, Austria.
Background: Cannabis and its derivatives show encouraging therapeutic effects in the treatment of various diseases. However, further studies are needed to better assess their efficacy and safety. A promising base for research in the field of medicine and additional pharmacovigilance is social networks, in which experience and knowledge are exchanged between researchers, doctors, and patients, as well as information about the potential risks and benefits of using drugs for medical purposes is disseminated.
View Article and Find Full Text PDFPractitioners' perspectives on unintended effects of illicit drug use prevention public service announcements in Australia.
Health Promot Int
December 2024
Centre for Social Impact, College of Business, Government and Law, Flinders University, Sturt Road, Bedford Park, South Australia 5042, Australia.
Public service announcements (PSAs) or campaigns aimed at preventing harm can inadvertently risk creating additional harms. It remains unclear whether these unintended effects are considered during campaign development, if risk mitigation strategies are implemented, or how professionals involved perceive these issues. It is in the context of illicit drug use prevention PSAs that our research investigates and explores the perspectives of practitioners-health support professionals and advertising campaign designers and creators.
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