The following method of examination of patients with chronic primary gastroduodenitis is proposed: 1) clinical examination; 2) roentgen and endoscopic examination; 3) assessment of genetic predisposition to ulcer disease; 4) examination of the acid- and pepsin-forming gastric function; 5) determination of the pepsin aggression ratio; 6) determination of the gastric juice defense ratio; 7) biochemical examination of the amino acid composition of the gastric mucosa; 8) determination of the lipid peroxidation intensity. The obtained data indicate that chronic primary gastroduodenitis is not a pre-disease but an initial stage of ulcer disease.

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