Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1089/cap.2010.2032 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A case of an unusual presentation of obsessive compulsive disorder in an adolescent.
Asian J Psychiatr
June 2019
Colombo South Teaching Hospital, Kalubowila, Dehiwala, Sri Lanka. Electronic address:
Children and adolescents with Obsessive Compulsive Disorder (OCD) can present in atypical and unusual ways. We present the case of a 13 year old boy with an unusual presentation of OCD. He presented with irritability, aggression, poor sleep, reduced attention, hyperreligiosity, social withdrawal and disinhibition (i.
View Article and Find Full Text PDFAntipsychotic agents in the treatment of anorexia nervosa: neuropsychopharmacologic rationale and evidence from controlled trials.
Curr Psychiatry Rep
August 2012
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA.
The search for an effective psychopharmacologic strategy in the treatment of anorexia nervosa (AN) has been elusive for decades and has run the gamut from reserpine to typical antipsychotics, to lithium, to tetrahydrocannabinol, to growth hormone, to anticonvulsants, to antidepressants, to atypical antipsychotics. Only recently has there arisen a potential "diamond in the rough" in the form of the atypical antipsychotic agent, olanzapine, which, in four randomized clinical trials, has shown superiority to placebo (two studies), chlorpromazine (one study), and aripiprazole (one study) in terms of weight gain and/or reduction in obsessional symptoms. The pharmacologic profile of olanzapine and other antipsychotic medications is discussed in light of the known pathophysiology of AN involving serotonin and dopamine systems, as well as brain-derived neurotrophic factor.
View Article and Find Full Text PDFObsessive-compulsive symptoms in schizophrenia: prevalence, clinical features and treatment. A literature review.
World J Biol Psychiatry
January 2012
Abarbanel Mental Health Centre, Bat Yam, Israel.
Objectives: To investigate the prevalence of obsessive-compulsive symptoms in schizophrenia, the clinical features of the sub-group of patients with schizophrenia and obsessive-compulsive symptoms and treatment options for these patients.
Method: A literature review of studies investigating the prevalence, clinical features and treatment of patients with schizophrenia and obsessive-compulsive symptoms.
Results: The prevalence of obsessive-compulsive symptoms in schizophrenic patients, while generally found to be higher than in the general population, varies widely between different studies.
The most common type of FTLD-FUS (aFTLD-U) is associated with a distinct clinical form of frontotemporal dementia but is not related to mutations in the FUS gene.
Acta Neuropathol
July 2011
Mental Health and Neurodegeneration Research Group, Faculty of Human and Medical Sciences, University of Manchester, Manchester, UK.
Frontotemporal lobar degeneration (FTLD) is clinically, pathologically and genetically heterogeneous. Recent descriptions of a pathological sub-type that is ubiquitin positive, TDP-43 negative and immunostains positive for the Fused in Sarcoma protein (FUS) raises the question whether it is associated with a distinct clinical phenotype identifiable on clinical grounds, and whether mutations in the Fused in Sarcoma gene (FUS) might also be associated with FTLD. Examination of a pathological series of 118 cases of FTLD from two centres, showing tau-negative, ubiquitin-positive pathology, revealed FUS pathology in five patients, four classified as atypical FTLD with ubiquitin inclusions (aFTLD-U), and one as neuronal intermediate filament inclusion disease (NIFID).
View Article and Find Full Text PDFObsessional and atypical tic symptoms in an adolescent with complex Tourette's disorder and atypical pervasive developmental disorder not otherwise specified.
J Child Adolesc Psychopharmacol
June 2010
NYU Child Study Center, New York, NY 10016, USA.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!