Objective: To determine the frequency, risk factors, and visual outcome of post traumatic endophthalmitis in children.
Methods: The study was conducted on patients less than fifteen years age, presenting with penetrating ocular injuries and associated with endophthalmitis. Anterior segment slit lamp examination and if possible posterior segment slit lamp examination with 90 D fundoscopes was performed. After completing necessary investigations, urgent surgical intervention was carried out.
Results: There were 43 registered patients with 29 (67.4%) males and 14 (32.6%) females. Twenty three (53.4%) children presented on the day of injury. Remaining 20 (46.6%) reported after first 24 hours. Twenty seven (62.7%) children presented with corneal wound, 11 (25.6%) had scleral entrance, and 5 (11.7%) patients had corneo scleral extension. Nineteen (44.1%) patients developed clinical evidence of endophthalmitis. Fifteen subjects with endophthalmitis completed six weeks follow up. Two (13.3%) subjects achieved final visual acuity (FVA) of 3/60. Four (26.7%) had only hand movements, 5 (33.4%) subjects were restricted to perception of light, and 2 (13.3%) patients developed phthisis bulbi.
Conclusion: Delayed arrival of patients in eye hospital with open globe injury may result in endophthalmitis
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ACS Appl Mater Interfaces
January 2025
Department of Microsystems Engineering (IMTEK), Laboratory for Chemistry & Physics of Interfaces (CPI), Albert Ludwigs Universität Freiburg, Georges Köhler Allee 103, 79110 Freiburg, Germany.
Glaucoma, a leading cause of blindness, demands innovative and effective treatments that surpass the limitations of current drug and surgical interventions to lower intraocular pressure. This study describes the generation of cell-repellent hydrogel patches, their deposition on the ocular surface, and a photoinduced chemical binding between the patches and the collagens of the eye. The hydrophilic and protein-repellent hydrogel patch is composed of a copolymer made from dimethylacrylamide and a comonomer unit with anthraquinone moieties.
View Article and Find Full Text PDFEye Contact Lens
January 2025
Medical College of Wisconsin, Milwaukee, WI.
Purpose: To describe a rare case of infectious keratitis secondary to Brevundimonas diminuta, a gram-negative bacillus with fluoroquinolone resistance and rare clinical isolation.
Methods: A 50-year-old man with contact lens overuse presented with a large corneal ulcer and hand motion visual acuity. Initial treatment with fortified topical tobramycin and vancomycin yielded slow improvement, and initial culture grew Staphylococcus epidermidis, Staphylococcus hominis, and Corynebacterium bovis.
Biomedicines
January 2025
Institute of Ophthalmology, University of Modena and Reggio Emilia, Azienda Ospedaliero-Universitaria di Modena, 41122 Modena, Italy.
Background/objectives: Micropulse laser trabeculoplasty (MLT) is gaining attention as a non-invasive treatment option for primary open-angle glaucoma (POAG), offering an alternative to traditional surgeries and medications. This systematic review evaluates the effectiveness, safety, and potential of MLT in glaucoma management.
Methods: This review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
Antioxidants (Basel)
December 2024
College of Public Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Particulate matter (PM), particularly fine (PM) and ultrafine (PM) particles, originates from both natural and anthropogenic sources, such as biomass burning and vehicle emissions. These particles contain harmful compounds that pose significant health risks. Upon inhalation, ingestion, or dermal contact, PM can penetrate biological systems, inducing oxidative stress, inflammation, and DNA damage, which contribute to a range of health complications.
View Article and Find Full Text PDFHealthcare (Basel)
January 2025
Emergency Department, CHU UCL Namur, 5530 Yvoir, Belgium.
Penetrating orbit injury is a rare but complex and life-threatening occurrence that may easily be overlooked. Management in the emergency department requires an early multidisciplinary approach but still lacks standard guidelines. This narrative review aims to provide a systematic approach to the management of penetrating orbital injuries for emergency clinicians.
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