Metastatic epidural spinal cord compression is a debilitating consequence of multiple cancer types. Early diagnosis and treatment are imperative for improving functional outcome. The authors review the epidemiology, pathophysiology, clinical features, and diagnostic evaluation of metastatic epidural spinal cord compression. Special attention will be given to the supportive and definitive treatments available for management, and new therapeutic interventions, such as radiosurgery, will be briefly discussed as well.
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http://dx.doi.org/10.1055/s-0030-1255221 | DOI Listing |
Sci Rep
January 2025
Department of Anaesthesiology, Affiliated Hospital of North Sichuan medical college, Nanchong, Sichuan, China.
The effect of epidural infusion of dexmedetomidine on haemodynamics is unclear. This study aimed to explore the effects of epidural or intravenous infusion of dexmedetomidine on haemodynamics during lower extremity varicose veins surgery (saphenectomy) under epidural anaesthesia. Ninety patients were randomly allocated to three groups: ED group (epidural: 0.
View Article and Find Full Text PDFEur J Clin Pharmacol
January 2025
Department of Anesthesiology, the Second Afffliated Hospital of Soochow University, Suzhou City, People's Republic of China.
Objective: In part I, measure the EC50 of sufentanil in obese and non-obese parturients combined with 0.1% ropivacaine and compare the differences. Similarly, in part II, measure the EC50 of ropivacaine in obese and non-obese parturients combined with 0.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland.
: Esophagectomy is a key component of esophageal cancer treatment, with minimally invasive esophagectomy (MIE) increasingly replacing open esophagectomy (OE). Effective postoperative pain management can be achieved through various analgesic modalities. This study compares the efficacy of thoracic epidural anesthesia (TEA) with non-TEA methods in managing postoperative pain following MIE.
View Article and Find Full Text PDFCancers (Basel)
December 2024
Department of Neurosurgery, University of Marburg, 35037 Marburg, Germany.
Background: The aim of this study was to assess the surgical outcomes and survival of patients surgically treated for metastatic epidural spinal cord compression (MESCC), with a specific focus on identifying factors that influence overall survival and readmission-free survival.
Methods: All patients who underwent surgery for spine metastases at our department in the period 2018-2022 were included in the study.
Results: A total of 175 patients (n = 71 females, median age 67.
Cureus
December 2024
Anesthesiology and Perioperative Medicine, Medical University of South Carolina, Charleston, USA.
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