Purpose: In endoscopic ENT surgery, the identification and localization of target structures is challenging-depth information is missing, relevant tissues could be hidden behind opaque material and image distortion affects the instrument handling. In this paper, a novel overlay visualization is presented that supports the surgeon by superimposing planning and navigation information on the endoscopic image.
Method: Target regions, which have been identified in preoperative CT data, are superimposed on the endoscopic image, allowing the use of guiding lines for distance visualization. To match the overlay information with the geometrically distorted endoscopic images, a new intraoperative calibration procedure has been developed.
Results: The accuracy of this new method has been verified by cadaver studies. Clinical evaluation in three paranasal sinus interventions was performed to show the intraoperative assistance and practicability with promising results.
Conclusion: The new techniques safely support the surgeon in locating target structures in the paranasal sinuses with little change in the actual workflow.
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http://dx.doi.org/10.1007/s11548-010-0507-7 | DOI Listing |
Nat Commun
January 2025
Proteomics and Bioanalytics, School of Life Sciences, Technical University of Munich, Freising, Germany.
Post-translational modifications (PTMs) play pivotal roles in regulating cellular signaling, fine-tuning protein function, and orchestrating complex biological processes. Despite their importance, the lack of comprehensive tools for studying PTMs from a pathway-centric perspective has limited our ability to understand how PTMs modulate cellular pathways on a molecular level. Here, we present PTMNavigator, a tool integrated into the ProteomicsDB platform that offers an interactive interface for researchers to overlay experimental PTM data with pathway diagrams.
View Article and Find Full Text PDFCancers (Basel)
December 2024
Radiation Oncology Department, Centre Frederic Joliot, 76000 Rouen, France.
Background/objectives: An on-board imager on a linear accelerator allows the acquisition of kV-2D images during irradiation. Overlaying specific structures on these images enables the visual verification of movement at regular frequencies. Our aim was to validate this tracking method for the stereotactic treatment of bone metastases.
View Article and Find Full Text PDFInt J Comput Assist Radiol Surg
January 2025
Department of Medical Biophysics, University of Toronto, Toronto, Canada.
Environ Monit Assess
January 2025
Technische Hochschule Nürnberg Georg Simon Ohm, Institute of Hydraulic Engineering and Water Resources Management, Nuremberg, Germany.
Through the mobilization of movable objects due to the extreme hydraulic conditions during a flood event, blockages, damage to infrastructure, and endangerment of human lives can occur. To identify potential hazards from aerial imagery and take appropriate precautions, a change detection tool (CDT) was developed and tested using a study area along the Aisch River in Germany. The focus of the CDT development was on near real-time analysis of point cloud data generated by structure from motion from aerial images of temporally separated surveys, enabling rapid and targeted implementation of measures.
View Article and Find Full Text PDFSci Rep
January 2025
Department Ophthalmology and Visual Sciences, McGill Vision Research, McGill University, Montreal, QC, Canada.
In amblyopia, abnormal binocular interactions lead to an overwhelming dominance of one eye. One mechanism implied in this imbalance is the suppression between the inputs from the two eyes. This interocular suppression involves two components: an overlay suppression and a surround suppression.
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