Introduction: The medical management of secondary hyperparathyroidism in patients with end-stage renal disease involves a combination of dietary restrictions, phosphate binders, active vitamin D analogs, and calcimimetics.
Case Presentation: We report the case of a 36-year-old Hispanic dialysis patient, originally from Cuba and now residing in the USA, who developed severe bone pain and muscle twitching after starting low dose cinacalcet, despite normal pre-dialysis ionized calcium and elevated parathyroid hormone. The clinical symptoms correlated with increased symmetrical uptake on bone scan that resolved rapidly upon discontinuation of cinacalcet.
Conclusion: Cinacalcet may induce severe bone pain and a unique bone scan uptake pattern in hemodialysis patients.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907400 | PMC |
| http://dx.doi.org/10.1186/1752-1947-4-191 | DOI Listing |
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