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Efficacy, acceptability, and safety of muscle relaxants for adults with non-specific low back pain: systematic review and meta-analysis.
BMJ
July 2021
Centre for Pain IMPACT, Neuroscience Research Australia, Sydney, NSW, Australia
Objective: To investigate the efficacy, acceptability, and safety of muscle relaxants for low back pain.
Design: Systematic review and meta-analysis of randomised controlled trials.
Data Sources: Medline, Embase, CINAHL, CENTRAL, ClinicalTrials.
[Methotrexate use: untangling the real from the fake].
Rev Med Suisse
June 2021
Clinique de rhumatologie, HFR Fribourg - Hôpital cantonal, 1708 Fribourg.
Methotrexate is one of the most important treatments for rheumatologists, however often of great concern to the non-specialist. This article reviews some useful aspects to know, in terms of safety with no major infectious risk or risk of pulmonary fibrosis, but also the benefits of using the subcutaneous route, the addition of low dose folic acid, the association with hydroxychloroquine or a short stop with flu vaccination, practical elements to demystify a safe and useful treatment.
View Article and Find Full Text PDFBayesian spatial modelling of terrestrial radiation in Switzerland.
J Environ Radioact
July 2021
Institute for Social and Preventive Medicine (ISPM), University of Bern, Switzerland. Electronic address:
The geographic variation of terrestrial radiation can be exploited in epidemiological studies of the health effects of protracted low-dose exposure. Various methods have been applied to derive maps of this variation. We aimed to construct a map of terrestrial radiation for Switzerland.
View Article and Find Full Text PDFAnalgesic medicines for adults with low back pain: protocol for a systematic review and network meta-analysis.
Syst Rev
November 2020
School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, Australia.
Background: There is limited evidence for the comparative effectiveness of analgesic medicines for adults with low back pain. This systematic review and network meta-analysis aims to determine the analgesic effect, safety, acceptability, effect on function, and relative rank according to analgesic effect, safety, acceptability, and effect on function of a single course of [an] analgesic medicine(s) or combination of these medicines for people with low back pain.
Methods: We will include published and unpublished randomised trials written in any language that compare an analgesic medicine to either another medicine, placebo/sham, or no intervention in adults with low back pain, grouped according to pain duration: acute (fewer than 6 weeks), sub-acute (6 to 12 weeks), and chronic (greater than 12 weeks).
Morphological and Transcriptomic Analysis of the Inhibitory Effects of on Growth and Aflatoxin Production.
Toxins (Basel)
November 2019
Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs/Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
, as a natural bio-preservative, has attracted a great deal of attention in recent years. In this study, 22 L strains were tested against the aflatoxin-producing fungus, ; strain IAMU80070 showed the highest antifungal activity. At a concentration of 5 × 10 colony-forming units (CFU) mL, it completely inhibited growth and decreased aflatoxin production by 93%.
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