Background: Infant mortality remains high in many developing countries in which the contribution of deaths among infants born very low birth weight (VLBW) may be considerable. This contribution has however not been quantified in most such countries. This paper explores a model that can be used in this respect.
Objective: To determine the contribution of very low birth weight infants towards the overall infants deaths in Kenya.
Design: Prospective cohort study.
Setting: Kenyatta National Hospital, Pumwani Maternity Hospital and Kilifi District Hospital.
Subjects: Very low birth weight infants followed up for a period of one year.
Results: The neonatal, post-neonatal and infant mortalities for the cohort were 442, 139 and 581/1000 respectively. These were thirteen, three and seven times higher than the national averages respectively. Of the national birth cohort of 1,300,000 during that year, it was estimated that between 15,600 (1.2%) and 24,700 (1.9%) were born VLBW. Given this VLBW infant burden and extrapolating the infant mortality observed in this study to the general population, between 9,064 (8.9%) and 14,351(14.2%) of the 101,400 (78/1000) infants who die during infancy in the country are born VLBW.
Conclusion: The cohort reports very high infant mortality for VLBW infants when compared to the general population. Despite constituting less than 2% of the birth cohort, these infants contribute between 8.9% and 14.2% of all infant deaths.
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http://dx.doi.org/10.4314/eamj.v86i8.54157 | DOI Listing |
Cent Eur J Public Health
December 2024
Department of Preclinical Subjects, Faculty of Health Sciences, Palacky University Olomouc, Olomouc, Czech Republic.
Objective: Pregnancy at advanced maternal age has become more common over the last decades. Therefore, the study aimed to describe the characteristics and maternal and perinatal outcomes of women giving birth at advanced maternal age and very advanced age.
Methods: We conducted a retrospective cohort study of 2,300 singleton births that occurred in 2020-2021 at the Department of Gynaecology and Obstetrics of the Louis Pasteur University Hospital in Košice.
Matern Child Health J
January 2025
Department of Nursing for Community-based Integrated Care, Division of Integrated Health Sciences, Nagoya University Graduate School of Medicine, 1-1-20 Daiko- Minami, Higashi-ku, Nagoya City, Aichi Prefecture, Japan.
Objectives: To determine the association between mothers' persistent maternal depression and their toddlers' behavior.
Methods: Online surveys were conducted twice with mothers who gave birth to their first child between March and June 2020. The survey periods were November 2020 and May-June 2022.
J Hum Reprod Sci
December 2024
Department of Reproductive Medicine, Gunasheela Surgical and Maternity Hospital, Bengaluru, Karnataka, India.
Background: Cancer treatments such as chemotherapy and radiotherapy often compromise fertility by damaging gonadal function, creating a critical need for fertility preservation options. Despite advancements in fertility preservation techniques, there is a significant lack of research focused on their application in Asian cancer patients and their utilisation remains underexplored in this population.
Aim: This study aims to evaluate the utilisation rates and outcomes of cryopreserved gametes in cancer patients who underwent fertility preservation before their cancer treatment.
Patient Prefer Adherence
January 2025
West China School of Nursing/ West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Purpose: Gout is a common, chronic inflammatory joint disease, and men are more likely to suffer from gout. Improving patient self-management behaviors is a priority in gout healthcare. Psychological capital is associated with self-management behaviors in chronic diseases and can be improved through a number of interventions.
View Article and Find Full Text PDFMaternal exposures are known to influence the risk of isolated cleft lip with or without cleft palate (CL/P) - a common and highly heritable birth defect with a multifactorial etiology. To identify new CL/P risk loci, we conducted a genome-wide gene-environment interaction (GEI) analysis of CL/P on a sample of 540 cases and 260 controls recruited from the Philippines, incorporating the interaction effects of genetic variants with maternal smoking and vitamin use. As GEI analyses are typically low in power and the results can be difficult to interpret, we used multiple testing frameworks to evaluate potential GEI effects: 1 degree-of-freedom (1df) GxE test, the 3df joint test, and the two-step EDGE approach.
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