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Tracking transmission through transposable elements in uropathogenic and commensal .
Future Microbiol
January 2025
Universidad San Francisco de Quito, Colegio de Ciencias Biológicas Ambientales, Instituto de Microbiología, Quito, Ecuador.
Aim: To investigate the nucleotide sequences associated with transposable elements carrying bla allelic variants as potential markers for the transmission of antimicrobial resistance genes between domestic animals, humans and the environment.
Materials & Methods: We conducted whole-genome sequencing and analyzed the nucleotide sequences of most abundant bla allelic variants (bla, bla, and bla) in commensal Escherichia coli ( = 20) from household members in Quito and uropathogenic E. coli (UPEC) ( = 149) isolated from nine clinics in Quito, Ecuador.
Debate: Where to next for universal school-based mental health interventions?
Child Adolesc Ment Health
February 2025
The Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.
In this article, we evaluate the current state of universal school-based mental health prevention. We argue that the field is at another pivotal turning point, with many unanswered questions. As youth mental health issues rise in prominence and prevalence, schools increasingly adopt mental health and well-being programmes.
View Article and Find Full Text PDFHigher Aircraft Noise Exposure Is Linked to Worse Heart Structure and Function by Cardiovascular MRI.
J Am Coll Cardiol
December 2024
UCL MRC Unit for Lifelong Health and Ageing, University College London, London, United Kingdom; UCL Institute of Cardiovascular Science, University College London, London, United Kingdom; Centre for Inherited Heart Muscle Conditions, Cardiology Department, Royal Free Hospital, London, United Kingdom. Electronic address:
Background: Aircraft noise is a growing concern for communities living near airports.
Objectives: This study aimed to explore the impact of aircraft noise on heart structure and function.
Methods: Nighttime aircraft noise levels (L) and weighted 24-hour day-evening-night aircraft noise levels (L) were provided by the UK Civil Aviation Authority for 2011.
Efficacy of Early Goal-Directed Therapy in Septic Shock Management: A Systematic Review.
Cureus
November 2024
Obstetrics and Gynecology, Private Clinic "Yana Alexandr", Sana'a, YEM.
Septic shock is a serious and life-threatening illness marked by potentially fatal and metabolic abnormalities, leading to high mortality rates in adult patients. Early goal-directed therapy (EGDT) was introduced as a systematic approach to manage septic shock through early, protocol-based hemodynamic optimization to improve outcomes. This systematic review aims to evaluate the efficacy of EGDT in managing adult patients with septic shock.
View Article and Find Full Text PDFAn exploratory case study of food sharing practices in Caribbean countries through a transition lens using intergenerational dyad interviews.
Global Health
December 2024
European Centre for Environment & Human Health, University of Exeter Medical School, Penryn, UK.
Background: Caribbean populations face complex health issues related to diet and food security as they undergo a rapid nutrition transition, resulting in some of the world's highest number of premature deaths from noncommunicable diseases (NCDs). Despite policy efforts to promote local and regional food consumption, reliance on food imports remains high with many Caribbean countries importing more than 80% of their food from larger economies. Previous regional research revealed the importance of food sharing practices in the Caribbean, with implications for the consumption of local foods, food security, and community resilience against climate change.
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