Aims: The study aimed to evaluate psychometrically a Danish translation of the Short Alcohol Withdrawal Scale (SAWS) in an outpatient setting in patients with Alcohol Dependence (AD) and Alcohol Withdrawal Symptoms/Syndrome (AWS).
Methods: One hundred and twenty-two patients with AD and AWS filled in a 10-item rating scale to describe their symptoms with four graduations on five physical and five psychological items. The question of dimensionality of the construct was addressed in three different ways. First, a scree plot was constructed based on the polychoric correlations between items. Second, promax factor loadings were calculated for a two-factor model. These two steps were based on exploratory factor analysis. Third, specific violations such as local dependence and differential item functioning were investigated under the one-factor model in a confirmatory factor analysis.
Results: The scree plot supported one or two dimensions while the promax rotations gave little support for a two-factor model. The confirmatory analysis also supported a one-factor model.
Conclusion: The decomposition of the polychoric correlation matrix into eigenvalues and vectors suggested that there was most likely one factor underlying the 10 items in the SAWS. This was confirmed by a confirmative factor analysis with only one component when specific model violations such as local dependence and differential item findings were investigated. The SAWS is easy to use.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/alcalc/agq033 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Impact of Prenatal Dietary Soy on Cerebellar Neurodevelopment and Function in Experimental Fetal Alcohol Spectrum Disorder.
Nutrients
February 2025
Departments of Neuroscience and Biology, Brown University, Providence, RI 02903, USA.
Prenatal alcohol exposure (PAE) models can cause neurodevelopmental abnormalities like those observed in fetal alcohol spectrum disorder (FASD). Previous studies link experimental PAE effects in the brain to impaired signaling through insulin/IGF and Notch pathways that mediate neuronal survival, growth, migration, energy metabolism, and plasticity. Importantly, concurrent administration of peroxisome proliferator-activated receptor agonists or dietary soy prevented many aspects of FASD due to their insulin-sensitizing, anti-inflammatory, and antioxidant properties.
View Article and Find Full Text PDFPharmaceutical Automated Reporting: An opioid stewardship tool.
J Opioid Manag
March 2025
Stewardship and Clinical Appropriateness, Saskatchewan Health Authority, Regina, Sas-katchewan, Canada. ORCID: https://orcid.org/0009-0005-2332-3923.
Objective: To develop and implement a customized clinical decision support system (CDSS) in an under-resourced health region aimed at promoting appropriate and safe opioid prescribing.
Design: The Pharmaceutical Automated Reporting (PAR) tool integrates inpatient prescription data from BDM Pharmacy (version 10) and categorizes patient information using predefined logic. It operates with Python (version 3.
Prevalence of Patients Admitted to Intensive Care After Administration of Chlordiazepoxide in the Emergency Room.
Basic Clin Pharmacol Toxicol
April 2025
Department of Clinical Pharmacology, Aarhus University Hospital, Aarhus, Denmark.
Chlordiazepoxide is effective in treating alcohol withdrawal syndrome, but it poses a risk of long-term sedation. The prevalence of this side effect and its risk factors remain uncertain. This retrospective cross-sectional study aimed to estimate both using data from Aarhus University Hospital's BI portal.
View Article and Find Full Text PDFRetrospective analysis of low-dose versus higher-dose haloperidol in older emergency department patients.
Am J Emerg Med
March 2025
Upstate University Hospital, Department of Pharmacy, 750 E Adams St, Syracuse, NY 13210, USA.
Background: A reduced initial dose of injectable haloperidol is recommended in older patients for treatment of acute agitation based on limited studies.
Objective: Assess the effectiveness and safety of higher-dose versus low-dose injectable haloperidol in older patients presenting to the emergency department (ED).
Methods: This was a retrospective, propensity-score matched, cohort analysis conducted at a two-campus healthcare system.
Development of a sample preparation and analysis method for therapeutic monitoring of diazepam and major metabolite in alcohol withdrawal syndrome treatment.
J Pharm Biomed Anal
March 2025
Department of Forensic Toxicology, Institute of Forensic Sciences, Ankara University, Ankara 06620, Turkiye. Electronic address:
Diazepam, a widely prescribed benzodiazepine, is frequently used for the management of alcohol withdrawal syndrome, anxiety, seizures, and muscle spasms. Its monitoring is critical due to its potential for abuse and the therapeutic importance of its metabolite nordiazepam. A sustainable and environmentally friendly high-performance liquid chromatography method was developed and validated for the quantification of diazepam and its active metabolite nordiazepam in human plasma samples.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!