Exercise induced bronchconstriction (EIB) is defined as a transient increase in airway resistance reflected as at least a 10% decline in FEV1 following at least 6-8 minutes of strenuous exercise. Up to 90% of asthmatics, 45% of individuals with allergic rhinitis, 50% of Olympic athletes, and 12% of the general population have EIB. EIB in adolescence may be either under- or over-diagnosed because of denial of symptoms or misperception of dyspnea or other respiratory symptoms. Diagnosis cannot always rely on history alone and may require an objective exercise challenge or surrogate measure. Management of EIB may require reduction in the exercise provoking the asthma but it can usually be successfully managed with training and the appropriate use of medications, including inhaled beta-agonists, inhaled steroids, and/or leukotriene antagonists. Nonpharmacologic therapy with face masks, warming up and down, and calisthenics may also be an effective adjunct in reducing medication needs. For most adolescents, proper pharmacotherapy will provide complete control of the airway and a normal healthy lifestyle without exercise restrictions.
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J Hypertens
November 2024
Faculty of Sport Sciences, Universidad Europea de Madrid.
Objectives: The effects of acute physical exercise in patients with resistant hypertension remain largely unexplored compared with hypertensive patients in general. We assessed the short-term effects of acute moderate-intensity (MICE) and high-intensity interval exercise (HIIE) on the clinic (BP) and 24-h ambulatory blood pressure (ABP) of patients with resistant hypertension.
Methods: Using a crossover randomized controlled design, 10 participants (56 ± 7 years) with resistant hypertension performed three experimental sessions: MICE, HIIE, and control.
J Physiol
January 2025
Laboratory of Developmental Biology and Genomics, Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Exercise provides health benefits to multiple metabolic tissues through complex biological pathways and interactions between organs. However, investigating these complex mechanisms in humans is still limited, making mouse models extremely useful for exploring exercise-induced changes in whole-body metabolism and health. In this review, we focus on gaining a broader understanding of the metabolic phenotypes and molecular mechanisms induced by exercise in mouse models.
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January 2025
Institute of Sports and Arts Convergence, Inha University, Incheon, Republic of Korea.
Introduction: Exercise is vital in preventing and treating obesity. Despite its importance, the understanding of how exercise influences childhood obesity at the biochemical level is limited. In this study, we explore the effects of a 16-week exercise program (EP) on body composition, physical fitness, and the blood levels of hormones related to obesity.
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December 2024
Department of Physiotherapy, Faculty of Health Sciences, University of Pretoria, Pretoria North, South Africa.
Background: HIV-associated neurocognitive disorder (HAND) affects an individual's capacity for independence and engagement in everyday activities, posing challenges in environments with limited resources and low social support.
Objectives: To ascertain the efficacy of exercise (AE) for activity and participation (AP) level in people with HAND.
Method: This is a randomised controlled trial that is parallel-group in nature, with intention-to-treat analysis and disguised allocation.
Physiol Rep
January 2025
United States Department of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center, Grand Forks, North Dakota, USA.
Exercise counters many adverse health effects of consuming a high-fat diet (HFD). However, complex molecular changes that occur in skeletal muscle in response to exercising while consuming a HFD are not yet known. We investigated the interplay between diverse exercise regimes and HFD consumption on the adaptation of skeletal muscle transcriptome.
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