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Prevalence of Second Primary Malignancies in Patients With Well-Differentiated Neuroendocrine Tumors.
Endocr Pract
January 2025
Department of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznan, Poland.
Objective: Neuroendocrine tumors (NETs) constitute a diverse group of tumors. NETs are often diagnosed late, due to nonspecific symptoms. Second Primary Malignancies (SPMs) have been reported in up to 25% of NETs and their incidence has been described as negative predictor of overall survival.
View Article and Find Full Text PDFAGA Clinical Practice Update on Screening and Surveillance in Individuals at Increased Risk for Gastric Cancer in the United States: Expert Review.
Gastroenterology
February 2025
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Palo Alto, California.
Description: Gastric cancer (GC) is a leading cause of preventable cancer and mortality in certain US populations. The most impactful way to reduce GC mortality is via primary prevention, namely Helicobacter pylori eradication, and secondary prevention, namely endoscopic screening and surveillance of precancerous conditions, such as gastric intestinal metaplasia (GIM). An emerging body of evidence supports the possible impact of these strategies on GC incidence and mortality in identifiable high-risk populations in the United States.
View Article and Find Full Text PDFPleural carcinoid diagnosed via video-assisted thoracoscopy biopsies in a patient with recurrent unilateral pleural effusion at St. Francis hospital Nsambya: a case report.
J Med Case Rep
December 2024
RineCynth Advisory Limited, Kampala, Uganda.
Background: Pulmonary carcinoids are rare neuroendocrine tumors accounting for less than 1% of all lung cancers. They are classified into two subcategories; typical and atypical carcinoids with the latter tending to grow faster. Historically, open thoracotomy was the standard approach for pulmonary resection.
View Article and Find Full Text PDFAdenocarcinoma of the rete testis: clinicopathological study of 18 cases with emphasis on MET amplification and a review of the literature.
Histopathology
December 2024
State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Background: Knowledge regarding adenocarcinoma of the rete testis (ACRT) is extremely limited due to its scarcity.
Methods And Results: This study enrolled 18 patients with ACRT from multiple institutions. Clinicopathological and immunohistochemical features were investigated, together with a comprehensive review of 95 previously reported cases.
First Report of Response to Tarlatamab in a Patient With DLL3-Positive Pulmonary Carcinoid: Case Report.
JTO Clin Res Rep
December 2024
Department of Pharmacy Services, UVA Health, Charlottesville, Virginia.
Article Synopsis
- * The effectiveness of tarlatamab in other cancer types, like DLL3-expressing metastatic pulmonary carcinoid tumors, was previously unknown and lacked approved treatment options.
- * A patient with a metastatic atypical carcinoid tumor responded positively to tarlatamab after failing several other treatments, suggesting potential benefits for other pulmonary neuroendocrine cancers.
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