[Validation of the ABCDI and ABCD2I scales in the registry of patients with transient ischemic attacks from Lleida (REGITELL) Spain].

Med Clin (Barc)

Sección de Neurología, Unidad de Ictus, Hospital Universitari Arnau de Vilanova de Lleida, Universitat de Lleida, Institut de Recerca Biomédica de Lleida (IRBLLeida), Lleida, Spain.

Published: September 2010

AI Article Synopsis

  • A new radiological-clinical score called ABCDI was evaluated to predict stroke recurrence risk after a transient ischemic attack (TIA) in a study involving 310 patients.
  • The study found that the recurrence rates at 7 days and 90 days were relatively low, with specific factors like previous episodes and atheromatous etiology being significant predictors of stroke recurrence.
  • Ultimately, the research concluded that the ABCDI and ABCD2I scores were not effective in accurately assessing stroke recurrence risk in this patient group, indicating the need for a more comprehensive evaluation beyond just clinical scores or CT findings.

Article Abstract

Background And Objectives: A new radiological-clinical score (ABCDI) has been recently described to predict the risk of stroke recurrence after a transient ischemic attack (TIA). We validated this score in a cohort of patients with TIA (REGITELL).

Patients And Methods: We studied 310 consecutive patients with TIA. Clinical scales (ABCD and ABCD2) and radiological-clinical scales (ABCDI and ABCD2I) were quantified. Radiological clinical scales were calculated by adding one point for the presence of ischemic brain injury in CT scan to its eponymous clinical score. We established its relationship with the risk of recurrence at 7 and 90 days, and the presence of an atheromatous etiology (AE).

Results: During the first week of follow-up, 18 (5.8%) patients suffered a recurrence, whereas 24 (7.7%) had a recurrence at 90 days. The multivariate study (Cox regression) identified the recurrence of episodes (hazard ratio [HR] 2.92, 95% CI 1.11 to 7.64, p=0.029) and AE (HR 3.13 95% CI: 1.17 to 8.36, p=0.023) as independent predictors of new stroke at 7 days and only AE for stroke at three months (RR 3.33, 95% CI: 1,42-7,77, p=0.006). The predictors (logistic regression) of AE were recurrence of episodes (odds ratio [OR] 3.12, 95% CI 1.58-6.14, p=0.001) and presence of ischemic lesions on CT scan (OR 2.69, 1.38-5.28, p=0.004).

Conclusions: The ABCDI and ABCD2I scales are not useful in our population. The risk of recurrence after a TIA cannot only be established by clinical scores or CT scan findings.

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Source
http://dx.doi.org/10.1016/j.medcli.2009.10.054DOI Listing

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