The career of Richard J. Stull, II, president and chief executive officer of North Broward Hospital in Fort Lauderdale, FL, reflects the solid grounding he received, literally starting on his father's knee. Dick's career is unusual from another perspective; he moved through the ranks to a distinguished career in one location. A young man still, he speaks of looking back after the next 15 years and saying, "I laid out the vision, plotted the course and stayed to make it happen." We need more leaders with a long vision and the commitment to stay and make things happen.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/00004010-199101620-00013 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
SARS-CoV-2 Viral Load in the Nasopharynx at Time of First Infection Among Unvaccinated Individuals: A Secondary Cross-Protocol Analysis of 4 Randomized Trials.
JAMA Netw Open
May 2024
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington.
Importance: SARS-CoV-2 viral load (VL) in the nasopharynx is difficult to quantify and standardize across settings, but it may inform transmission potential and disease severity.
Objective: To characterize VL at COVID-19 diagnosis among previously uninfected and unvaccinated individuals by evaluating the association of demographic and clinical characteristics, viral variant, and trial with VL, as well as the ability of VL to predict severe disease.
Design, Setting, And Participants: This secondary cross-protocol analysis used individual-level data from placebo recipients from 4 harmonized, phase 3 COVID-19 vaccine efficacy trials sponsored by Moderna, AstraZeneca, Janssen, and Novavax.
Risk of COVID-19 after natural infection or vaccination.
EBioMedicine
October 2023
Department of Pediatrics, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA.
Article Synopsis
- Study explores the protective effects of previous SARS-CoV-2 infection and hybrid immunity (infection plus vaccination) against COVID-19, using data from various vaccine trials.
- Participants were grouped based on their previous infection status and whether they received a vaccine, with a main focus on confirmed COVID-19 cases post-treatment.
- Results indicated that individuals with previous infections had a significantly lower risk of contracting COVID-19, and hybrid immunity generally offered better protection than vaccination alone, emphasizing the effectiveness of both natural infection and vaccination in preventing severe disease.
Clinical and Demographic Factors Associated With COVID-19, Severe COVID-19, and SARS-CoV-2 Infection in Adults: A Secondary Cross-Protocol Analysis of 4 Randomized Clinical Trials.
JAMA Netw Open
July 2023
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington.
Importance: Current data identifying COVID-19 risk factors lack standardized outcomes and insufficiently control for confounders.
Objective: To identify risk factors associated with COVID-19, severe COVID-19, and SARS-CoV-2 infection.
Design, Setting, And Participants: This secondary cross-protocol analysis included 4 multicenter, international, randomized, blinded, placebo-controlled, COVID-19 vaccine efficacy trials with harmonized protocols established by the COVID-19 Prevention Network.
Intestinal Gpr17 deficiency improves glucose metabolism by promoting GLP-1 secretion.
Cell Rep
January 2022
Herman B. Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Medical Neuroscience Graduate Program, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Department of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Electronic address:
G protein-coupled receptors (GPCRs) in intestinal enteroendocrine cells (EECs) respond to nutritional, neural, and microbial cues and modulate the release of gut hormones. Here we show that Gpr17, an orphan GPCR, is co-expressed in glucagon-like peptide-1 (GLP-1)-expressing EECs in human and rodent intestinal epithelium. Acute genetic ablation of Gpr17 in intestinal epithelium improves glucose tolerance and glucose-stimulated insulin secretion (GSIS).
View Article and Find Full Text PDFA high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues.
J Biol Chem
January 2022
Stark Neurosciences Research Institute, Medical Neuroscience Graduate Program, Indiana University School of Medicine, Indianapolis, Indiana, USA; Herman B. Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA; Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA; Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA; Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA; Department of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA. Electronic address:
Insulin resistance impairs postprandial glucose uptake through glucose transporter type 4 (GLUT4) and is the primary defect preceding type 2 diabetes. We previously generated an insulin-resistant mouse model with human GLUT4 promoter-driven insulin receptor knockout (GIRKO) in the muscle, adipose, and neuronal subpopulations. However, the rate of diabetes in GIRKO mice remained low prior to 6 months of age on normal chow diet (NCD), suggesting that additional factors/mechanisms are responsible for adverse metabolic effects driving the ultimate progression of overt diabetes.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!