Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
KLRB1 expression in nasopharyngeal mucosa as a prognostic biomarker in COVID-19 patients.
Sci Rep
January 2025
Research and Innovation Unit, Costa del Sol University Hospital, Autovía A-7, km 187, Marbella, 29603, Spain.
The resurgence of COVID-19 and the rise in severe outcomes emphasize the need for reliable prognostic markers to guide patient care and optimize ICU and hospital resources. This study investigates the potential of nasopharyngeal swabs to identify biomarkers that predict ICU admission or death in hospitalized COVID-19 patients. We analyzed nasopharyngeal exudates from 95 hospitalized patients in 2020 using high-plex RNA quantification on the NanoString nCounter platform.
View Article and Find Full Text PDFPortrait of a Cerebral Killer.
Diagnostics (Basel)
January 2025
Vietnam Research and Development Institute of Clinical Microbiology, Ho Chi Minh City 700000, Vietnam.
: Primary amebic meningoencephalitis (PAM) caused by is a rare and devastating infection of the central nervous system, often diagnosed late, due to its rapid progression and nonspecific symptoms. We report one of the youngest documented pediatric Vietnamese cases of PAM in a 10-month-old girl from the Mekong Delta, Vietnam. The diagnosis was confirmed through multiplex real-time PCR (MPL-rPCR), microscopy, and sequencing.
View Article and Find Full Text PDFAuthor Correction: Metaproteomic portrait of the healthy human gut microbiota.
NPJ Biofilms Microbiomes
January 2025
Department of Biomedical Sciences, University of Sassari, Sassari, Italy.
Transcriptomic analysis of skeletal muscle regeneration across mouse lifespan identifies altered stem cell states.
Nat Aging
December 2024
Genetics, Genomics and Development Graduate Program, Cornell University, Ithaca, NY, USA.
In aging, skeletal muscle regeneration declines due to alterations in both myogenic and non-myogenic cells and their interactions. This regenerative dysfunction is not understood comprehensively or with high spatiotemporal resolution. We collected an integrated atlas of 273,923 single-cell transcriptomes and high-resolution spatial transcriptomic maps from muscles of young, old and geriatric mice (~5, 20 and 26 months old) at multiple time points following myotoxin injury.
View Article and Find Full Text PDFIn situ chemoproteomic profiling reveals itaconate inhibits de novo purine biosynthesis in pathogens.
Cell Rep
September 2024
Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China; Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. Electronic address:
Itaconate serves as an immune-specific metabolite that regulates gene transcription and metabolism in both host and pathogens. S-itaconation is a post-translational modification that regulates immune response; however, its antimicrobial mechanism under the physiological condition remains unclear. Here, we apply a bioorthogonal itaconate probe to perform global profiling of S-itaconation in living pathogens, including S.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!