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Disulfiram-induced neuropathy: a case report.

Gen Hosp Psychiatry

September 2015

Mental Health Institute, S.C.B. Medical College, Cuttack, Odisha, India, 753007.

Disulfiram is widely used for aversive treatment of alcoholism. Neuropathy is one of the most severe side effects of disulfiram therapy. We report the case of a young man who developed a neuropathy following disulfiram administration, with a virtually complete recovery within 2 months.

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Disulfiram is an alcohol-deterring agent with few rare serious adverse effects, usually dose-related, reversible, and more frequent with comorbid alcohol and nicotine dependence. We report a prospective follow-up of such a case with reversible peripheral neuropathy and irreversible optic neuropathy.

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[Disulfiram-induced polyneurophaty].

Vojnosanit Pregl

May 2012

Neuroloska klinika, Klinicki centar Crne Gore, Podgorica, Crna Gora.

Introduction: Disulfiram is used in the treatment of chronic alcoholism, because of the unpleasant symptoms produced after ethanol intake. Although it is well tolerated in most patients, one in 15,000 patients will develop peripheral neuropathy every year, which is frequently misdiagnosed as alcoholic neuropathy.

Case Report: We report clinical, laboratory, electrophysiological and histopathological features in a 19-year-old patient who developed an acute distal sensorymotor neuropathy during the treatment of alcoholism.

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Disulfiram-induced transient optic and peripheral neuropathy: a case report.

Ir J Med Sci

December 2007

Department of Ophthalmology, Waterford Regional Hospital, Dunmore Road, Waterford, Republic of Ireland.

Aim: To report a case of optic and peripheral neuropathy after chronic use of disulfiram for alcohol dependence management.

Materials And Methods: A case report.

Results: A 57-year-old male presented with gradual loss of vision in both eyes with intermittent headaches for 2 months.

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