AI Article Synopsis
- Low-frequency vibrations (20 Hz, A = 0.4 mm) significantly boost GABA levels and the activity of the glutamate decarboxylase enzyme in various brain regions of adult male rats.
- The increases in GABA and enzyme activity are most pronounced after 30 minutes of vibration exposure, showing less effect after longer durations (7 hours and 30 days).
- Additionally, the levels of glutaminic and aspartic acids rise after 30 minutes but decline after prolonged vibration exposure (7 hours and 30 days).
Article Abstract
Low-frequency vibration, irrespective of its duration (20 Hz, A = 0.4 mm), is shown to increase GABA level, glutamatedecarboxylase enzyme activity (EC 4.1.1.15) in the large hemispheres, cerebellum, brain stem of adult male rats (12 months). Meanwhile GABA aminotransferase activity (EC 2.6.1.19) remains, mainly, unchanged. The observed shifts are more clear under 30 min vibration than under 7h and 30 day effects. Glutaminic and aspartic acids content increases under 30 min and decreases under 7h and 30 day vibration in the given brain structures.
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