[Uncontrolled chronic glycaemia in diabetic patients with neoplasm increases the risk of early surgical complications].

Rev Med Inst Mex Seguro Soc

Servicio de Medicina Interna, Hospital de Oncología, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Distrito Federal, México.

Published: September 2010

Background: The effect of uncontrolled chronic glycemia (UCG) in the diabetic patient with a neoplasm (DPN) has not been evaluated during the early postoperative period. Our objective was to determine the frequency of early surgical complications in the DPN with UCG.

Methods: A cohort of 184 consecutive diabetic patients who had a histological malignant diagnosis were studied; they were matched with 184 non-diabetic controls by age, gender, neoplasm type and surgery, those who received chemotherapy or irradiation 30 days before surgery were excluded. Fasting blood glucose, HbA1c, presence of diabetic complications and co-morbidity before surgery; type of surgery and postoperative early morbidity and mortality were measured.

Results: The DPN with UCG had a higher frequency of surgical postoperative complications than their controls. The presence of comorbidity (p < 0.011) and HbA1c > 6.5 % (p < 0.011) were independent and ominous significant predictors.

Conclusions: Preoperative UCG increases the risk of early surgical complications in DPN.

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