Unlabelled: We prospectively evaluated a novel nano-synthesized, membrane-covered self-expanding super-elastic all-metal endoprosthesis stent (SESAME Stent) in patients undergoing percutaneous intervention (PCI) of degenerated saphenous vein graft (SVG) lesions.
Methods: SESAME investigators prospectively enrolled 20 patients/21 lesions at 2 outside United States (OUS) centers, between February 2005 and August 2005. Patients underwent elective intervention of symptomatic SVG lesions with ≥ 50% stenosis. PCI was performed without embolic protection devices. The primary end point was technical and procedural success. Secondary end points included major adverse cardiac events (MACE) at 30 days and 9 months.
Results: Twenty patients (twenty-one SVG lesions) received SESAME stents. The acute success was 100%. No procedural or in hospital complications occurred. One patient underwent a planned staged PCI at 28 days in a separate SVG. Follow-up was present in 20 patients at 30 days, with clinical (n = 19) and angiographic evaluation (18 patients/19 lesions) at 9 months. No MACE events occurred at 30 days. At 9 months, 3 patients underwent repeat PCI. One TLR (restenosis at the overlap of two stents) and two nonindex lesion TVR for a MACE rate of 14% at 9 months.
Conclusions: This study demonstrated the ABPS SESAME Stent has excellent acute success, low 30 day MACE rates and 9 month patency of the SESAME is similar to balloon expandable stents without embolic protection.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/ccd.22687 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Modest dilation using rotational atherectomy and drug-coated balloon for native coronary proximal lesion with patent internal thoracic artery graft.
J Cardiol Cases
December 2024
Department of Cardiology, Kyoto Saiseikai Hospital, Nagaokakyo, Japan.
Unlabelled: Intervention to proximal lesions should be avoided in graft-protected native coronary arteries in general, because there might be a risk for bypass-graft failure. An 81-year-old man with coronary artery bypass grafting surgery due to 3-vessel disease 17 years previously complained of worsening angina. Coronary angiography (CAG) revealed a diseased saphenous vein graft (SVG) and a probable functional occlusion in the mid left anterior descending coronary artery (LAD) concomitant with calcified severe stenosis in the left main (LM)-proximal LAD, and patent right internal thoracic artery (RITA)-LAD graft.
View Article and Find Full Text PDFOutcome of Saphenous Vein Graft Percutaneous Coronary Intervention Using Contemporary Drug-Eluting Stents: A SCAAR Report.
J Soc Cardiovasc Angiogr Interv
October 2024
Department of Cardiology, Västerås Hospital, Västerås, Sweden.
Background: Percutaneous coronary intervention (PCI) of saphenous vein grafts (SVG) is associated with poor outcomes and is often regarded as inferior to native vessel PCI. We investigated clinical outcomes of SVG-PCI using contemporary drug-eluting stents (DES), in a complete, nationwide population.
Methods: The complete Swedish Coronary Angiography and Angioplasty Registry (SCAAR) was used to identify all patients in Sweden who underwent SVG-PCI with a contemporary DES between 2013 and 2020.
The Role of Advanced Glycation End Products in Saphenous Vein Graft Failure.
Med Princ Pract
October 2024
Department of Cardiology, Faculty of Medicine, Bandırma Onyedi Eylül University, Balıkesir, Turkey.
Objective: We aimed to investigate the relationship between advanced glycation end product (AGE) levels in patients with saphenous vein graft (SVG) failure and in patients without SVG failure.
Subjects And Methods: In our study, 55 patients with a history of previous coronary artery bypass grafting (CABG) surgery, who subsequently underwent coronary angiography for any reason and were found to have either SVG occlusion or significant lesions, were included as study patients. Additionally, 55 patients who have had CABG surgery without SVG failure for at least 1 year served as the control group.
Role of Embolic Protection in Percutaneous Coronary Intervention without Saphenous Venous graft lesions in ST-elevation myocardial infarction - a systematic review and meta-analysis.
Crit Pathw Cardiol
October 2024
-Jacobi Medical Center Department of Medicine 1400 Pelham Pkwy S, Bronx, New York 10461.
Article Synopsis
- - Embolic protection devices (EPDs) are used during percutaneous coronary interventions (PCI) to catch debris that can cause complications; this study focused on their effectiveness and safety in ST-elevation myocardial infarction (STEMI) patients without saphenous vein grafts (SVG).
- - Researchers analyzed data from three randomized controlled trials (RCTs) involving 741 patients, examining multiple outcomes including 30-day mortality and major adverse events following PCI with and without EPDs.
- - Results showed that while EPDs did not significantly affect overall mortality or other major outcomes like heart flow and ST segment resolution, they did significantly lower the incidence of detectable distal embolization.
Successful Intravascular Lithotripsy Use for Acute Stent Underexpansion in Saphenous Vein Grafts.
J Soc Cardiovasc Angiogr Interv
February 2024
Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Experience with intravascular lithotripsy (IVL) following stent deployment in saphenous vein graft (SVG) lesions is limited. We present 2 cases of percutaneous intervention in SVG in which acute stent underexpansion was successfully managed with IVL. In the first case, recalcitrant plaque required prestent deployment IVL, with intracoronary imaging showing persistent calcification.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!