A case of adams-oliver syndrome.

Ann Dermatol

Department of Dermatology, Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea.

Published: February 2010

Adams-Oliver syndrome (AOS) is a congenital condition characterized by aplasia cutis congenita, transverse limb defects, and cutis marmorata telangiectatica. AOS can also be associated with extensive lethal anomalies of internal organs, including the central nervous, cardiopulmonary, gastrourointestinal, and genitourinary systems. Generally, the more severe these interrelated anomalies are, the poorer the prognosis becomes. In the relevant literature on this topic, it is somewhat unclear as to whether the prognosis of AOS without lethal anomalies alters the lifespan. We report a case of AOS with typical skin defects only, and no internal organ anomalies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883411PMC
http://dx.doi.org/10.5021/ad.2010.22.1.96DOI Listing

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