AI Article Synopsis
- The study investigated how often abnormal echocardiographic findings occur in patients with tuberous sclerosis complex, analyzing data from 56 patients who underwent screenings between 1995 and 2003.
- Two researchers reviewed the echocardiogram results, finding that 39% of patients had abnormal findings, with the most prevalent issue being focal areas of increased echogenicity in the heart muscle, observed in 29% of patients.
- The researchers concluded that such echocardiographic abnormalities are relatively common among individuals with tuberous sclerosis complex, although the clinical significance of these findings remains unclear.
Article Abstract
We sought to examine the frequency of abnormal echocardiographic findings in patients with tuberous sclerosis complex. In a retrospective cohort study, we included all patients with known tuberous sclerosis complex who had been sent to our cardiology department for echocardiographic screening from 1995 through August 2003 (n=56). Two research scientists independently reviewed the reports of the echocardiographic screening examinations for abnormal findings. We used descriptive statistics, the Mann-Whitney U test, and the chi(2) test. The mean age of patients included in the study was 35 years (range, 12-73 yr); 23 patients were male. Abnormal findings were seen in 22 patients (39%). The most common abnormal findings were focal areas of increased intramyocardial echogenicity, which were seen in 16 patients (29%). The clinical consequence of this finding is still unknown. We conclude that echocardiographic abnormalities are common in patients with tuberous sclerosis complex.
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