A patient with lichen sclerosus, Langerhans cell histiocytosis, and invasive squamous cell carcinoma of the vulva.

Michiel Simons Hedwig P Van De Nieuwenhof Irene A M Van Der Avoort Johan Bulten Joanne A De Hullu

Am J Obstet Gynecol

Department of Obstetrics and Gynecology, Catharina Hospital, Eindhoven, The Netherlands.

Published: August 2010

We report a patient with vulvar lichen sclerosus, Langerhans cell histiocytosis (LCH), and later vulvar cancer. In LCH, high amounts of non functional Langerhans cells are present in the affected tissue, making it possible that LCH may have contributed to vulvar cancer development in this patient.

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http://dx.doi.org/10.1016/j.ajog.2010.04.023	DOI Listing

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