We utilize spatial and angular diversity to achieve speckle reduction in laser illumination. Both free-space and imaging geometry configurations are considered. A fast two-dimensional scanning micromirror is employed to steer the laser beam. A simple experimental setup is built to demonstrate the application of our technique in a two-dimensional laser picture projection. Experimental results show that the speckle contrast factor can be reduced down to 5% within the integration time of the detector.
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http://dx.doi.org/10.1364/AO.49.003297 | DOI Listing |
Echocardiography
January 2025
Department of Ultrasound, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Objectives: Supra-normal left ventricular ejection fraction (snLVEF) represents a heterogeneous group with distinct prognoses. Left atrial (LA) strain, measured by speckle tracking echocardiography (STE), is a validated prognostic indicator. This study aimed to evaluate LA and left ventricular (LV) mechanical strains in hypertensive patients with snLVEF.
View Article and Find Full Text PDFNeurobiol Dis
January 2025
Department of Molecular Genetics & Microbiology, University of Florida College of Medicine, Gainesville, FL 32611, USA.
Abnormal tau phosphorylation is a key mechanism in neurodegenerative diseases. Evidence implicates infectious agents, such as Herpes Simplex Virus 1 (HSV-1), as co-factors in the onset or the progression of neurodegenerative diseases, including Alzheimer's disease. This has led to divergence in the field regarding the contribution of viruses in the etiology of neurodegenerative diseases.
View Article and Find Full Text PDFBiomed Opt Express
January 2025
Faculty of Biomedical Engineering, Technion-Israel Institute of Technology, Haifa 3200003, Israel.
In fiber-based confocal microscopy, using two separate fibers for illumination and collection enables the use of a few-mode fiber to achieve an effect similar to opening the pinhole in a conventional confocal microscope. In some Fourier-domain applications, however, or when a spectral measurement is involved, the coherent light detection would lead to noticeable spectral modulation artifacts that result from differential mode delay, an effect caused by the multimode propagation in the collection fiber. After eliminating these artifacts by using mode-dependent polarization control, we demonstrate effective spectrally encoded imaging with improved signal efficiency and lower speckle noise, and only a minor, negligible reduction in lateral and axial resolutions.
View Article and Find Full Text PDFJ Gastrointest Oncol
December 2024
Department of Intervention, Yancheng First People's Hospital, Yancheng, China.
Background: Hepatocellular carcinoma (HCC) is characterized by high postoperative recurrence rates, and predicting early recurrence is crucial for improving clinical outcomes, yet remains challenging. Both preoperative computed tomography (CT) imaging radiomic features and serum biomarkers related to microvascular infiltration are important indicators of HCC prognosis. This study aimed to develop a nomogram model incorporating both preoperative CT radiomic features and serum biomarkers associated with microvascular infiltration to predict early postoperative recurrence in HCC patients.
View Article and Find Full Text PDFERJ Open Res
January 2025
Critical Care Department, Hospital Garcia de Orta EPE, Almada, Portugal.
Introduction: The number of vertical artefacts (VAs) in lung ultrasound (LUS) impacts patients' clinical management. This study aimed to demonstrate the influence of ultrasound settings on the number of VAs in patients under invasive mechanical ventilation (IMV).
Methods: Patients under IMV were recruited for LUS, including three breathing cycles with a motionless curvilinear probe on the thoracic region with the most VAs.
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