[Nail abnormality].

Rev Med Interne

Service de médecine interne, hôpital Saint-Antoine, Assistance publique-Hôpitaux de Paris, université Pierre-et-Marie-Curie, 75012 Paris cedex, France.

Published: February 2011

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.revmed.2009.08.022DOI Listing

Publication Analysis

Top Keywords

[nail abnormality]
4
[nail
1

Similar Publications

Introduction: Patients with end-stage renal disease usually undergo hemodialysis as a way of renal function replacement therapy which comes with a wide array of systemic and cutaneous complications. The aim of this study was to evaluate the most frequent dermatological manifestations including xerosis, pruritis and other nail, hair and oral conditions, as these are a very important aspect to be considered while managing the patients psychological and physical needs to improve their outcomes and quality of life.

Methods: This retrospective cross-sectional study was performed by selecting 77 patients on hemodialysis based on a certain criteria and data was then collected on a sheet using patients database on Hakeem National E-Health Program, in addition to information from interviews with patients during their hemodialysis sessions after taking an oral informed consent and insuring patients' privacy.

View Article and Find Full Text PDF

Impaired Wnt/Planar Cell Polarity Signaling in Yellow Nail Syndrome.

Ann Intern Med

January 2025

The Genetics Institute and Genomics Center, Tel Aviv Sourasky Medical Center, and School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel (H.B.F.).

Article Synopsis
  • Yellow Nail Syndrome (YNS) is a rare condition marked by yellow, malformed nails, swelling due to lymphedema, and chronic lung issues, typically presenting in adulthood, with potential genetic links suggested.
  • Researchers conducted genetic sequencing and expression studies on 11 patients (6 with congenital YNS and 5 with sporadic YNS) to investigate its underlying causes.
  • Findings revealed biallelic variants in genes related to the Wnt/planar cell polarity pathway in congenital cases, indicating that defects in cellular organization could be key to understanding YNS's development, though the study's small sample size is a limitation.
View Article and Find Full Text PDF
Article Synopsis
  • Cronkhite-Canada syndrome (CCS) is a rare gastrointestinal disorder characterized by taste abnormalities, observed in over 80% of cases, along with various ectodermal issues like nail atrophy and hair loss.
  • Ten diagnosed patients underwent assessments for taste function and other symptoms before and after treatment, revealing significant improvements in taste, especially in the anterior tongue.
  • The study shows that taste function tests are effective in measuring treatment outcomes, as patients experienced both symptom relief and improved taste function within three months post-treatment.
View Article and Find Full Text PDF

Chronic mucocutaneous candidiasis (CMC) is a primary immunodeficiency condition caused by a genetic abnormality that increases the risk of recurrent and persistent skin, nail, and mucous membrane infections with Candida species, typically . Signal transducer and activator of transcription 1 (STAT1) gene mutation is a genetic trigger that causes CMC, which increases the risk of infections, multisystem disorders, and cancer susceptibility. We describe the first case of a Saudi female patient with clinical features of CMC with an underlying (STAT1) gene mutation.

View Article and Find Full Text PDF

Background: Yellow nail syndrome is characterized by a yellow discoloration of the nails, respiratory symptoms, and lymphedema. It was first described in 1964 and has an estimated prevalence of less than 1:1.000.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!