Background: Seed localization uses a radioactive source to identify nonpalpable breast lesions for excision; it is an emerging alternative to wire localization (WL). Previous single health system studies report decreased rates of re-excision and improved patient convenience with this technique. This study is the first to implement this procedure in a public health care delivery system composed of a primarily minority and low-income population.
Materials And Methods: A multidisciplinary team was formed to create a protocol for breast seed localization (BSL) and monitor the results. After 50 seed localizations were successfully completed, a retrospective matched-pair analysis with patients who had undergone WL during the same period was performed.
Results: Overall experience with the BSL protocol is reviewed, along with the occurrence of a seed loss. Processes necessary to reactivate the BSL protocol and prevent future losses are delineated. BSL is associated with decreased rates of re-excision and can be successfully implemented in a public health care system.
Conclusions: BSL is an attractive alternative to WL in a high-volume, county-based population. It allows increased efficiency in the operating room and has a low rate of complications. Cautionary measures must be taken to ensure proper seed chain of custody to prevent seed loss.
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http://dx.doi.org/10.1245/s10434-010-1139-4 | DOI Listing |
Plant Foods Hum Nutr
January 2025
Facultad de Industrias Alimentarias, Universidad Nacional Agraria La Molina, Lima, Peru.
This review aimed to explore the impact of extrusion on Andean grains, such as quinoa, kañiwa, and kiwicha, highlighting their macromolecular transformations, technological innovations, and contributions to food security. These grains, which are rich in starch, high-quality proteins, and antioxidant compounds, are versatile raw materials for extrusion, a continuous and efficient process that combines high temperatures and pressures to transform structural and chemical components. Extrusion improves the digestibility of proteins and starches, encourages the formation of amylose-lipid complexes, and increases the solubility of dietary fiber.
View Article and Find Full Text PDFJ Integr Plant Biol
January 2025
School of Advanced Agricultural Sciences, Peking University, Beijing, 100871, China.
Heat stress (HS) at the reproductive stage detrimentally affects crop yields and seed quality. However, the molecular mechanisms that protect reproductive processes in plants under HS remain largely unknown. Here, we report that Acetylation Lowers Binding Affinity 3 (ALBA3) is crucial for safeguarding male fertility against HS in Arabidopsis.
View Article and Find Full Text PDFBrachytherapy
January 2025
Department of Radiology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of life Sciences and Medicine, University of Science and Technology, Hefei, Anhui 230022, PR China. Electronic address:
Purpose: To compare the effectiveness and safety of CT-guided iodine-125 seed brachytherapy in conjunction with chemotherapy against chemotherapy alone for the management of intermediate and advanced non-small cell lung cancer (NSCLC) lacking oncogenic driving genes.
Methods And Materials: Retrospective analysis was conducted on clinical data from 128 patients diagnosed with intermediate and advanced non-small cell lung cancer who received iodine-125 combined with chemotherapy or chemotherapy alone due to the absence of oncogenic driver gene mutations. The patients in two groups were compared at 6-month follow-up for objective remission rate (ORR), Disease control rate (DCR), local progression-free survival (LPFS), overall survival (OS), clinical symptom improvement, and adverse events.
Heliyon
January 2025
Jimma University, College of Agriculture and Veterinary Medicine, Department of Postharvest Management, P.O.Box:307, Jimma, Ethiopia.
is a tropical wild edible plant that is locally consumed in the Southern Nations, Nationalities, and Peoples Regional state of Ethiopia. However, there is limited information comparing nutritional, phytochemical, and anti-nutritional factors present in fruit pulps and seeds of the fruit. Therefore, this study aimed to investigate and compare the proximate compositions, phytochemical constituents, and anti-nutritional contents of the fruit pulp and seeds.
View Article and Find Full Text PDFBioData Min
January 2025
Department of Computer Science, Hanyang University, Seoul, Republic of Korea.
Background: Understanding the molecular properties of chemical compounds is essential for identifying potential candidates or ensuring safety in drug discovery. However, exploring the vast chemical space is time-consuming and costly, necessitating the development of time-efficient and cost-effective computational methods. Recent advances in deep learning approaches have offered deeper insights into molecular structures.
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