Gastric sarcoidosis and review of the literature.

J Natl Med Assoc

University of Southern California, Keck School of Medicine, Division of Pulmonary and Critical Care, 1200 N State St, GH 11900, Los Angeles, CA 90033, USA.

Published: May 2010

AI Article Synopsis

  • - Sarcoidosis primarily affects the lungs, but can involve any organ, with rare gastrointestinal involvement, typically affecting the stomach.
  • - Symptoms of gastrointestinal sarcoidosis can vary, including epigastric pain, nausea, vomiting, and sometimes hematemesis, with some patients experiencing no noticeable symptoms.
  • - The study presents two cases of gastric sarcoidosis and analyzes 44 reported cases, highlighting the importance of recognizing its clinical manifestations and endoscopic findings.

Article Abstract

Sarcoidosis is a systemic disease with a 90% predilection for the lungs, but any organ can be involved. Gastrointestinal involvement is rare. Within the gastrointestinal system, gastric involvement is the most common. When this organ system is involved, it can be a feature of systemic disease or an isolated case. Gastrointestinal sarcoid can resemble a broad spectrum of other disease processes; thus, it is important for health care providers to be familiar with the various gastrointestinal manifestations. Patients can have subclinical symptoms or have symptoms of epigastric pain, nausea, vomiting, and hematemesis. We present 2 cases of gastric sarcoid and a MEDLINE search of 44 reported cases of gastric sarcoid based on a compatible history and the demonstration of noncaseating granulomas. We describe the clinical manifestations of symptomatic gastric sarcoid in relation to the endoscopic findings.

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Source
http://dx.doi.org/10.1016/s0027-9684(15)30577-0DOI Listing

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