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Symptom Burden and Survivorship Care for Patients With Prostate Cancer on Androgen Deprivation Therapy.
J Natl Compr Canc Netw
December 2024
Dana-Farber Cancer Institute, Boston, MA.
Prostate cancer survivors represent a growing population of patients with a diagnosis of prostate cancer, whether they were cured using local therapies or continue to receive systemic treatment of advanced disease. Many patients receive androgen deprivation therapy (ADT) during treatment, which is associated with many long-lasting physical and psychological effects. Identifying and addressing the needs of survivors is imperative for improving their health and well-being.
View Article and Find Full Text PDFModifiable prognostic factors of high societal costs among people on sick leave due to musculoskeletal disorders: a replication study.
BMC Musculoskelet Disord
December 2024
Department of Rehabilitation Science and Health Technology, Oslo Metropolitan University, Oslo, Norway.
Background: Musculoskeletal disorders are an extensive burden to society, yet few studies have explored and replicated modifiable prognostic factors associated with high societal costs. This study aimed to replicate previously identified associations between nine modifiable prognostic factors and high societal costs among people on sick leave due to musculoskeletal disorders.
Methods: Pooled data from a three-arm randomised controlled trial with 6 months of follow-up were used, including 509 participants on sick leave due to musculoskeletal disorders in Norway.
Evaluating massage therapy for radiation-induced fibrosis in rats: preliminary findings and palpation results.
Cancer Biol Ther
December 2024
Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Radiation-induced fibrosis (RIF) is a common side effect of cancer treatment, but can manifest into a devastating syndrome for which there is no preventive measure or cure. In rats who perform a repetitive work task, who left untreated develop signs and symptoms that resemble repetitive motion disorders in humans, we have shown that manual therapy prevents the development of fibrosis and other key biomarkers. The fibrosis of RIF and repetitive motion disorders has similar biomarkers.
View Article and Find Full Text PDFSafety and efficacy of combined acetabular reconstruction and microwave ablation in the treatment of periacetabular metastatic disease: a retrospective clinical evaluation.
Front Oncol
October 2024
Department of Musculoskeletal Oncology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.
Article Synopsis
- The study examines the effectiveness of acetabular reconstruction using a reconstructive cage, combined with microwave ablation, for patients with periacetabular bone defects due to metastatic disease.
- In a review of 17 patients, results showed significant pain relief, with an average VAS score dropping from 7.7 to 2.2 post-surgery, and most patients able to walk independently or with aids.
- The overall survival rates indicated 40.9% at 12 months and 30.7% at 36 months, suggesting that this surgical method may offer benefits in pain management and functional recovery for selected patients.
MRI-guided neurolysis for the treatment of chronic refractory knee pain: a case report.
Skeletal Radiol
November 2024
Department of Diagnostic and Interventional Radiology, School of Medicine & Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.
Article Synopsis
- - The case report discusses a new treatment for chronic knee pain, particularly when other therapies have failed, highlighting a patient who underwent MRI-assisted chemical neurolysis targeting the genicular nerve.
- - A 62-year-old man experienced significant pain relief for four months after the procedure, suggesting that this method could be an effective option for those with persistent knee pain.
- - Despite promising results, further research, including controlled trials, is needed to fully assess the safety and effectiveness of this treatment before it can be commonly used in clinical practice.
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