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Deep learning model shows pathologist-level detection of sentinel node metastasis of melanoma and intra-nodal nevi on whole slide images.
Front Med (Lausanne)
August 2024
Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Introduction: Nodal metastasis (NM) in sentinel node biopsies (SNB) is crucial for melanoma staging. However, an intra-nodal nevus (INN) may often be misclassified as NM, leading to potential misdiagnosis and incorrect staging. There is high discordance among pathologists in assessing SNB positivity, which may lead to false staging.
View Article and Find Full Text PDFImproving skin cancer detection by Raman spectroscopy using convolutional neural networks and data augmentation.
Front Oncol
June 2024
Photomedicine Institute, Department of Dermatology and Skin Science, University of British Columbia and Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.
Article Synopsis
- The study investigates the effectiveness of combining deep neural networks and Raman spectroscopy to enhance skin cancer detection, demonstrating promising results in previous research.
- It analyzed the Raman spectra of 731 skin lesions, including both cancerous and benign types, using a 1D convolutional neural network for classification and various data augmentation strategies.
- Results showed that the performance metrics (ROC AUC) improved significantly after data augmentation, with the 1D-CNN achieving the highest score, indicating that this method could offer improved diagnostic accuracy for skin cancer detection.
The W-Plasty Serial Excision Method for Treating Medium Congenital Melanocytic Nevi: A Retrospective Analytical Study.
Dermatol Surg
October 2024
All authors are affiliated with the Department of Dermatology, Hangzhou Third People's Hospital, Hangzhou, Zhejiang, China.
Background: Serial excision remains the most commonly used surgical procedure for treating congenital melanocytic nevus (CMN). It is critical to remove as much of the lesion as possible with each procedure to reduce the number of procedures and to shorten the treatment duration.
Objective: To investigate the clinical efficacy of W-plasty serial excision for the repair of postoperative CMN defects.
Clinical study on the role of platelet-rich plasma in human acellular dermal matrix with razor autologous skin graft repair of giant congenital pigmented nevus in children.
J Plast Reconstr Aesthet Surg
March 2024
Department of Burns and Plastic Surgery, Beijing Children Hospital, National Center of Children's Health, Beijing Children Hospital, Capital Medical University, Beijing City, China. Electronic address:
Background: NA OBJECTIVE: Evaluate the safety and feasibility of platelet-rich plasma (PRP) in the treatment of giant congenital melanocytic nevi (GCMN) in children with human acellular dermal matrix (HADM) transplantation.
Patients And Methods: A total of 22 children with GCMN were included in the study. They were divided into an experimental and a control group.
Nevus of Ota: Combination Treatment with Q-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser and Fractional CO Laser.
J Cutan Aesthet Surg
January 2023
Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Background: Nevus of Ota is a facial dermal melanocytic hamartoma occurring more commonly in Asians. The mainstay of treatment is 1064-nm Q-Switched neodymium-doped yttrium aluminum garnet (Nd:YAG) laser, which has shown variable results in pigmented skin.
Objective: The aim of this study was to determine whether Q-Switched Nd:YAG laser treatment combined with fractional CO laser is more efficacious than Q-Switched Nd:YAG laser alone.
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