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High mobility group box 1 (HMGB1) mediates nicotine-induced podocyte injury.
Front Pharmacol
January 2025
Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, United States.
Introduction: Cigarette smoking is a well-established risk factor for renal dysfunction. Smoking associated with renal damage bears distinct physiological correlations in conditions such as diabetic nephropathy and obesity-induced glomerulopathy. However, the cellular and molecular basis of such an association remains poorly understood.
View Article and Find Full Text PDFElectronic cigarette use among adolescents in Saudi Arabia: A national study, 2022.
Tob Induc Dis
January 2025
General Directorate of Research and Studies, Ministry of Health, Riyadh, Saudi Arabia.
Introduction: Electronic cigarette (e-cigarette) use has increased globally among adolescents. However, data on its use among adolescents in Saudi Arabia remain limited. Therefore, this study describes the characteristics and factors associated with e-cigarette use in this population.
View Article and Find Full Text PDFPotential roles of cigarette smoking on gut microbiota profile among Chinese men.
BMC Med
January 2025
The Second Affiliated Hospital, School of Public Health, Zhejiang University School of Medicine, 388 Yuhangtang Road, Hangzhou, 310058, Zhejiang, China.
Background: Cigarette smoking is posited as a potential factor in disrupting the balance of the human gut microbiota. However, existing studies with limited sample size have yielded inconclusive results.
Methods: Here, we assessed the association between cigarette smoking and gut microbial profile among Chinese males from four independent studies (N total = 3308).
Relapse prevention among Iranian people who smoke through cognitive behavioral intervention: application of Marlatt's model.
BMC Psychiatry
January 2025
Department of Public Health, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: Relapse is by far the most likely outcome of any smoking cessation attempt. The present study aimed to assess the effectiveness of cognitive-behavioral intervention based on Marlatt's model on relapse prevention of people who smoke.
Methods: This interventional study was conducted among 265 people who smoke who referred to smoking cessation centers in Kurdistan province in Iran (intervention group = 129, control group = 136).
Mitochondrial DNA variants and their impact on epigenetic and biological aging in young adulthood.
Transl Psychiatry
January 2025
Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.
The pace of biological aging varies between people independently of chronological age and mitochondria dysfunction is a key hallmark of biological aging. We hypothesized that higher functional impact (FI) score of mitochondrial DNA (mtDNA) variants might contribute to premature aging and tested the relationships between a novel FI score of mtDNA variants and epigenetic and biological aging in young adulthood. A total of 81 participants from the European Longitudinal Study of Pregnancy and Childhood (ELSPAC) prenatal birth cohort had good quality genetic data as well as blood-based markers to estimate biological aging in the late 20.
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