Background: Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare and benign disease characterized by red to brown papules or nodules primarily in the head and neck region. Different treatment modalities including surgical excision, cryotherapy, chemotherapy, intralesional and systemic corticosteroids, curettage, electrodesiccation, radiation, and carbon dioxide, argon and pulsed dye lasers have been used with limited success; recurrences are common.
Case Report: We report a case of refractory ALHE who was successfully treated by surgery after several unsuccessful attempts with other conventional therapies.
Conclusion: We believe, in refractory cases of ALHE, surgery is still the logical and optimum treatment with fewer recurrences in the long term.
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