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| http://dx.doi.org/10.1111/j.1542-474X.2010.00348.x | DOI Listing |
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Classification of schwannomas and the new naming convention for "neurofibromatosis-2": Genetic updates and international consensus recommendation.
Neuroradiol J
January 2025
Department of Neuroradiology, Mayo Clinic, USA.
Despite their similar nomenclature, Neurofibromatosis type 1 (NF1) and "Neurofibromatosis type 2" are discrete and clinically distinguishable entities. The name of "neurofibromatosis type 2" has been changed to NF2-related schwannomatosis, to reflect the fact that neurofibromas do not occur in this syndrome and therefore the name "Neurofibromatosis" is factually incorrect. Furthermore, multiple schwannomas, a hallmark feature of NF2, can also occur in patients with mutations in genes including SMARCB1 and LZTR1, all exhibiting overlapping clinical features.
View Article and Find Full Text PDFThe National Institute on Aging and the Alzheimer's Association (NIA-AA) convened three separate work groups in 2011 and a single work group in 2018 to create recommendations for the diagnosis and characterization of Alzheimer's disease (AD). Several fundamental principles emerged from these efforts. These include, AD should be defined biologically, not by clinical syndromes.
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Alzheimers Dement
December 2024
University of British Columbia, Vancouver, BC, Canada.
Background: Social media provides dementia prevention researchers with additional opportunities to engage diverse audiences, including healthy individuals who unaware of their eligibility to take part in dementia-related research. However, practical social media guidance that reflects the values and priorities of potential participants is needed. To address this gap, we sought to create consensus recommendations with research professionals and community experts.
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Newcastle University, Newcastle Upon Tyne, United Kingdom.
Background: Older adults with dementia live with an average of four additional long-term conditions (multimorbidity), and experience frequent transitions between fragmented care settings. This can compromise their safety due to an increased risk of miscommunication, errors, and delays in receiving appropriate treatment. Unsafe transitions are also associated with increases in mortality, morbidity, and preventable readmissions.
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Alzheimers Dement
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Alzheimer's Disease Research Center, New York University Langone Health, New York, NY, USA.
Background: Behavioral and psychological symptoms of dementia (BPSD) occur frequently in persons with Alzheimer's disease (PAD). They cause suffering, institutionalization, carepartner distress, depression, burden, and decreased PAD-carepartner quality of life. Brexpiprazole approval advanced the AD treatment armamentarium.
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