AI Article Synopsis
- The study reports on the outcomes of penetrating keratoplasty (PK) in patients with active Acanthamoeba keratitis (AK) who did not improve with medical therapy.
- Nine patients underwent PK during the acute phase due to inadequate response to treatment, and the antiamoebic therapy was reduced post-surgery.
- After an average of 17 months, patients demonstrated good visual acuity and symptom resolution without recurrence, indicating that PK can be an effective option for severe cases of AK.
Article Abstract
Purpose: To report the results of penetrating keratoplasty (PK) in active Acanthamoeba keratitis (AK).
Methods: Nine patients with deep stromal infiltrates because of AK were treated with intensive antiamoebic medical therapy followed by PK during the acute infectious phase because of poor clinical response or poor compliance. Antiamoebic therapy was tapered after PK.
Results: Visual acuity ranged from 20/15 to 20/50 after an average of 17 months after PK with no signs of recurrences. Patients had rapid resolution of symptoms.
Conclusion: PK is a viable option for active AK not responding to maximum medical treatment.
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Source |
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| http://dx.doi.org/10.1097/ICO.0b013e3181cc79a1 | DOI Listing |
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