: Postirradiation morphea is a rare complication of radiation therapy which often presents as an erythematous indurated plaque and may be mistaken for recurrent or metastatic carcinoma. Histologic examination is essential for distinguishing postirradiation morphea from malignant processes and from other types of radiation dermatitis and infectious cellulitis. We report a case of postirradiation morphea and review the postirradiation morphea literature. In addition, we summarize the clinical and histopathologic characteristics of the various forms of postirradiation skin disease, including postirradiation morphea; acute, subacute, and chronic radiation dermatitis; and radiation recall dermatitis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/DAD.0b013e3181cb3fdd | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Characteristics of post-irradiation morphea in non-breast cancer patients.
Eur J Dermatol
October 2024
Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Post-Irradiation Morphea of the Breast in a Patient with Subacute Cutaneous Lupus Erythematosus: Case Report and a Literature Review.
Case Rep Dermatol
May 2022
Department of Dermatology, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
The appearance of morphea after radiotherapy, especially in the context of breast cancer, is a rare but known phenomenon. The incidence of post-irradiation morphea (PIM) of the breast is approximately one in every 500 patients, a higher rate than morphea of any other etiology, which is three per 100000 per year. PIM usually appears less than 1 year after irradiation (range 1 month to 32 years).
View Article and Find Full Text PDFIs it really post-irradiation morphea or oleoma of the breast?-A case report and literature review.
Gland Surg
December 2021
Department of Pathology, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, Changwon, Korea.
Article Synopsis
- - A 65-year-old woman developed skin changes, including hyperpigmentation and thickening, in her breast 10 years after having breast-conserving surgery and radiotherapy for cancer, raising concerns about several potential conditions including post-irradiation morphea and recurrent cancer.
- - Despite magnetic resonance imaging (MRI) showing no abnormalities, the patient experienced pain and worsening skin symptoms, leading to a simple mastectomy, which revealed oleoma and post-radiation fibrosis.
- - The case emphasizes the challenges in differentiating between post-irradiation morphea and oleoma due to the patient's complex medical history, highlighting the need for a multidisciplinary approach to ensure accurate diagnosis.
Case Report: Carcinoma en Cuirasse in a Middle-Aged Woman Mimicking Postirradiation Morphea.
Front Oncol
October 2021
Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Breast carcinoma en cuirasse (CeC) is an extremely rare form of cutaneous metastases of breast cancer, characterized by diffuse sclerodermoid induration of the skin. It may be difficult to distinguish CeC from some skin diseases, including postirradiation morphea, inflammatory breast cancer, radiation dermatitis, and other cutaneous metastases, but it can be easily discerned by histology. Because of the small number of documented cases, the treatment consensus has not been clearly defined.
View Article and Find Full Text PDFDermatologic sequelae of breast cancer: From disease, surgery, and radiation.
Int J Dermatol
April 2021
The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, NY, USA.
The care of breast cancer patients is important to dermatologists. Breast cancer's initial presentation, clinical progression, and its associated treatments can result in a variety of cutaneous complications. Dermatologists may be the first to identify a breast cancer diagnosis, as a subset of patients first present with direct extension of an underlying tumor or with a cutaneous metastasis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!