A new computer program has been developed designed to simulate all possible variants of nasal septum deformation and anatomical malformation of turbinate bones. Moreover, the program makes it possible to analyse approaches to surgical correction of these problems. Implications of this model for the practical treatment of patients with these disorders are discussed. The program provides a qualitatively new tool for obtaining a deeper insight into a given surgical intervention and facilitates mutual understanding between the surgeon and the patient. Also, it may be used as a teaching aid in the training of young ENT specialists.
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Nanoscale
January 2025
Instituto de Micro y Nanotecnología, IMN-CNM, CSIC (CEI UAM+CSIC) Isaac Newton, 8, Tres Cantos, Madrid, E-28760, Spain.
Three-dimensional magnetic nanowire networks (3DNNs) have shown promise for applications beyond those of their linear counterparts. However, understanding the underlying magnetization reversal mechanisms has been limited. In this study, we present a combined experimental and computational investigation on simplified 3DNNs to address this gap.
View Article and Find Full Text PDFACS Appl Bio Mater
January 2025
School of Materials Science and Physics, School of Chemical Engineering and Technology, China University of Mining and Technology, Xuzhou 221116, Jiangsu, China.
The application of a three-dimensional (3D)-printed biological functional scaffold in the repair of bone defects is a promising strategy. In this study, strontium-containing hydroxyapatite (SrHA) powder was synthesized by the hydrothermal method, and then poly(ε-caprolactone) (PCL)/HA and PCL/SrHA composite scaffolds were prepared by the high-temperature melt extrusion 3D printing technology. The basic physical and chemical properties, in vitro biological properties, osteogenesis, and angiogenesis abilities of the scaffold were studied.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Biomedical Engineering, Duke University, Durham, NC, USA.
Acoustically probing biological tissues with light or sound, photoacoustic and ultrasound imaging can provide anatomical, functional, and/or molecular information at depths far beyond the optical diffusion limit. However, most photoacoustic and ultrasound imaging systems rely on linear-array transducers with elevational focusing and are limited to two-dimensional imaging with anisotropic resolutions. Here, we present three-dimensional diffractive acoustic tomography (3D-DAT), which uses an off-the-shelf linear-array transducer with single-slit acoustic diffraction.
View Article and Find Full Text PDFeNeuro
January 2025
Department of Neuroscience, University of Connecticut School of Medicine, Farmington, Connecticut 06030
The study of the neural circuitry underlying complex mammalian decision-making, particularly cognitive flexibility, is critical for understanding psychiatric disorders. To test cognitive flexibility, as well as potentially other decision-making paradigms involving multimodal sensory perception, we developed FlexRig, an open-source, modular behavioral platform for use in head-fixed mice. FlexRig enables the administration of tasks relying upon olfactory, somatosensory, and/or auditory cues and employing left and right licking as a behavior readout and reward delivery mechanism.
View Article and Find Full Text PDFPhilos Trans A Math Phys Eng Sci
January 2025
KIOS Research and Innovation Center of Excellence (KIOS CoE) and Department of Electrical and Computer Engineering, University of Cyprus, Nicosia 1678, Cyprus.
This work proposes a coverage controller that enables an aerial team of distributed autonomous agents to collaboratively generate non-myopic coverage plans over a rolling finite horizon, aiming to cover specific points on the surface area of a three-dimensional object of interest. The collaborative coverage problem, formulated as a distributed model predictive control problem, optimizes the agents' motion and camera control inputs, while considering inter-agent constraints aiming at reducing work redundancy. The proposed coverage controller integrates constraints based on light-path propagation techniques to predict the parts of the object's surface that are visible with regard to the agents' future anticipated states.
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