Progress testing in the Netherlands was originally developed at Maastricht University. Since the late 1990s, a collaboration has started between three medical schools to jointly produce and administer the progress test. Currently, the progress test is administered to five out of eight medical schools in the Netherlands. The collaboration has led to substantial decrease in necessary resources per participating school. Also, the data provide a rich source for comparisons between schools and can be instrumental in inducing improvements to the curricula. Logistics of large-scale administrations and possible differences of views on item quality could be seen as a disadvantage. Also, it is not always easy to fit the test in the local regulatory structure, because it is only partly owned by each individual school. Important lessons for us have been that the advantages of the collaboration clearly outweigh the disadvantages. Of course, good collegial communication is needed, but this is not enough: a legal binding agreement has to be drawn up. Most importantly, such a collaboration creates a critical mass to enable multi-centre research and development projects on progress testing.
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http://dx.doi.org/10.3109/0142159X.2010.485658 | DOI Listing |
JCO Clin Cancer Inform
January 2025
Machine Learning Department, H. Lee Moffit Cancer Center and Research Institute, Tampa, FL.
Purpose: Adaptive radiotherapy accounts for interfractional anatomic changes. We hypothesize that changes in the gross tumor volumes identified during daily scans could be analyzed using delta-radiomics to predict disease progression events. We evaluated whether an auxiliary data set could improve prediction performance.
View Article and Find Full Text PDFPLoS One
January 2025
Centre for Regenerative Medicine and Devices, University of Brighton, Brighton, United Kingdom.
Diabetic foot, leg ulcers and decubitus ulcers affect millions of individuals worldwide leading to poor quality of life, pain and in several cases to limb amputations. Despite the global dimension of this clinical problem, limited progress has been made in developing more efficacious wound dressings, the design of which currently focusses on wound protection and control of its exudate volume. The present in vitro study systematically analysed seven types of clinically-available wound dressings made of different biomaterial composition and engineering.
View Article and Find Full Text PDFInt J Rheum Dis
January 2025
Department of Orthopedics, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Hubei, China.
Objective: Osteoarthritis is a common joint disease caused by a variety of risk factors, and it has been found that many biochemical markers are abnormal in peripheral blood and urine of patients with OA. The aim of this study was to elucidate the causal relationship between biomarkers associated with these processes and OA using Mendelian randomization (MR) analysis.
Method: The inverse variance weighted (IVW) approach to MR was primarily used to explore causal associations between exposures and outcomes using publicly available genetic variants from large genome-wide association studies (GWAS).
J Anat
January 2025
Institute of Sports Medicine Copenhagen, Department of Orthopedic Surgery, Copenhagen University Hospital - Bispebjerg-Frederiksberg, Copenhagen, Denmark.
Tendon injuries and disorders associated with mechanical tendon overuse are common musculoskeletal problems. Even though tendons play a central role in human movement, the intrinsic healing process of tendon is very slow. So far, it is known that tendon cell activity is supported by several interstitial cells within the tendon.
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