Basal cell carcinoma, the most common skin cancer, has several clinical and histopathological variants, with its most common form being nodular basal cell carcinoma. Fibroepithelioma of Pinkus is considered as an unusual variant of basal cell carcinoma by some authors while others consider it to be a benign analogue of basal cell carcinoma. We present a rare case of fibroepithelioma of Pinkus in continuity with a nodular basal cell carcinoma, a finding that supports the classification of fibroepithelioma of Pinkus as a variant of basal cell carcinoma.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1007/s12253-010-9284-4 | DOI Listing |
Metabolites
December 2024
Laboratory of Quality & Safety Risk Assessment for Aquatic Products, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Ministry of Agriculture and Rural Areas, Harbin 150070, China.
The salinization of the water environment worldwide is increasing, which has brought great challenges to the sustainability of fish farming of aquatic animals. Three NaHCO concentration groups (0 mmol/L, 20 mmol/L, and 60 mmol/L) were set up in this study to investigate growth and metabolic differences between diploid and triploid crucian carp under saline-alkaline stresses. This study utilized UPLC-QTOF/MS metabolomics to analyze significant metabolites and metabolic pathways in the serum of diploid and triploid crucian carp, exposing them to different NaHCO concentrations in saline-alkaline habitats, elucidating the mechanism of their metabolic differences.
View Article and Find Full Text PDFDermatopathology (Basel)
December 2024
Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL 33140, USA.
PRAME (PReferentially expressed Antigen in MElanoma) is a tumor-associated antigen first identified in tumor-reactive T-cell clones derived from a patient with metastatic melanoma. Immunohistochemistry (IHC) for PRAME is useful for diagnostic purposes to support a suspected diagnosis of melanoma. Anecdotally, PRAME has been observed to stain sebaceous units in glands in background skin.
View Article and Find Full Text PDFDermatopathology (Basel)
November 2024
Second Dermatology Department, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
The dermoscopic rainbow pattern (RP), also known as polychromatic pattern, is characterized by a multicolored appearance, resulting from the dispersion of polarized light as it penetrates various tissue components. Its separation into different wavelengths occurs according to the physics principles of scattering, absorption, and interference of light, creating the optical effect of RP. Even though the RP is regarded as a highly specific dermoscopic indicator of Kaposi's sarcoma, in the medical literature, it has also been documented as an atypical dermoscopic finding of other non-Kaposi skin entities.
View Article and Find Full Text PDFPlant Biotechnol J
December 2024
State Key Laboratory of Rice Biology (State Key Laboratory of Rice Biology and Breeding), China-IRRI Joint Research Center on Rice Quality and Nutrition, Key Laboratory of Rice Biology and Genetics Breeding of Ministry of Agriculture, China National Center for Rice Improvement, China National Rice Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou, China.
Enhanced grain yield and quality traits are everlasting breeding goals. It is therefore of great significance to uncover more genetic resources associated with these two important agronomic traits. Plant MYB family transcription factors play important regulatory roles in diverse biological processes.
View Article and Find Full Text PDFFEBS J
December 2024
Department of Neuroinflammation, UCL Queen Square Institute of Neurology, University College London, UK.
The microglial triggering receptor expressed on myeloid cells 2 (TREM2) is required for diverse microglia responses in neurodegeneration, including immunometabolic plasticity, phagocytosis, and survival. We previously identified that patient iPSC-derived microglia (iPS-Mg) harboring the Alzheimer's disease (AD) TREM2 hypomorph display several functional deficits linked to metabolism. To investigate whether these deficits are associated with disruptions in metabolite signaling, we generated common variant, TREM2 and TREM2 variant human iPS-Mg.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!