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Ethnobotany of vascular plants use, conservation and management practice in the homegardens by the people of Dawuro in Southwestern Ethiopia.
J Ethnobiol Ethnomed
January 2025
Department of Biology, College of Natural and Computational Science, Arba Minch University, Arba Minch, Ethiopia.
Background: Homegardens (HGs) are well-time-honored traditional land use systems in small plots of land with purposely designed intricate structure and a mixture of planted vascular plants (VPs) for different purposes. Hence, the present study was initiated to investigate the ethnobotanical information of vascular plants of homegardens and their use, conservation and management practice by the people of Dawuro in southwestern Ethiopia.
Methods: A total of 162 farmer informants were selected and interviewed within a distance of < 2 km, 2-4 km and > 4 km between the natural forest and homegardens, and 0.
Content analysis of perceptions of combined pharmacobehavioral treatment for American Indian people with opioid use disorder.
Psychol Addict Behav
January 2025
Department of Psychiatry and Behavioral Sciences, University of Washington.
Objective: Both opioid misuse and overdose mortality have disproportionately impacted the American Indian population. Although medications for opioid use disorder, such as buprenorphine (BUP-NX), are highly effective in reducing overdose mortality, questions have been raised about the cultural acceptability of Western medical approaches in this population. Understanding patients' desired recovery pathways can lead to more culturally appropriate, patient-centered, and effective approaches to opioid use disorder (OUD) treatment.
View Article and Find Full Text PDFLipid Nanoparticles Enable Efficient In Vivo DNA Knock-In via HITI-Mediated Genome Editing.
Biomolecules
December 2024
Graduate School of Engineering Science, Osaka University, Toyonaka 560-8531, Osaka, Japan.
In vivo genome editing holds great therapeutic potential for treating monogenic diseases by enabling precise gene correction or addition. However, improving the efficiency of delivery systems remains a key challenge. In this study, we investigated the use of lipid nanoparticles (LNPs) for in vivo knock-in of ectopic DNA.
View Article and Find Full Text PDFFrom Choice to Justice: Disrupting the Binary Political Logics of Assisted Reproduction.
Health Hum Rights
December 2024
Associate professor of women, gender, and sexuality studies in the Frederik Meijer Honors College at Grand Valley State University, Allendale, Michigan, United States.
Reproductive rights and reproductive justice paradigms have long been viewed as incompatible, largely because of their divergent orientations to the notion of choice. According to this oppositional framing, reproductive rights approaches have centered the right of (white, middle-class, heterosexual) women to choose not to have children while reproductive justice organizing has focused on gendered, racialized, and classed obstacles to control over whether and how to have and raise children. Amid increasing examination of assisted reproductive technologies (ARTs) vis-à-vis human rights principles, I see an opportunity to narrow the perceived gap between the politics of rights and justice.
View Article and Find Full Text PDFA stimuli-responsive drug delivery system based on konjac glucomannan, carboxymethyl chitosan and mesoporous polydopamine nanoparticles.
Int J Biol Macromol
December 2024
Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China. Electronic address:
A stimuli-responsive drug delivery system is developed for controlled delivery of curcumin (Cur) and chemo-photothermal therapy of breast cancer (BC). Cur is first loaded into mesoporous polydopamine nanoparticles (mPDA NPs) by π-π stacking, and then the Cur loaded mPDA NPs (mPDA NPs@Cur) are encapsulated in the hydrogels prepared through the crosslinking of oxidized konjac glucomannan (oxKGM) and carboxymethyl chitosan (CMCS). Owing to the pH-sensitivity of the hydrogels and the outstanding photothermal conversion capability of mPDA NPs, the release of Cur from the hydrogels can be greatly accelerated in acidic media upon near infrared (NIR) irradiation.
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