The incidence of subarachnoid hemorrhage is estimated at 5 to 10 per 100,000 per year. In patients who survive the initial hemorrhage, the repeat hemorrhage rate is 15% to 20% in the first 2 weeks after presentation and is associated with devastating clinical outcomes even graver than the initial rupture. The current options for aneurysm treatment are surgical clipping and, since the mid-1990s, neuroendovascular coil embolization. The former was at one time the gold standard of care, but consistent with the trend in modern medicine toward less-invasive procedures, the latter has steadily gained prominence. Although there is still controversy as to its long-term durability and safety, it is now the preferred procedure. This article describes the procedure's antecedents, rationale, and essential components. Mt Sinai J Med 77:279-285, 2010. (c) 2010 Mount Sinai School of Medicine.
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http://dx.doi.org/10.1002/msj.20183 | DOI Listing |
J Neurosurg
January 2025
2Department of Radiology, Service of Interventional Neuroradiology, Centre hospitalier de l'Université de Montréal (CHUM), Montréal.
Objective: Many patients with ruptured intracranial aneurysms (RIAs) underrepresented or excluded from previous randomized controlled trials (RCTs) comparing surgery with endovascular treatment (EVT) are still considered for surgical clipping, but the best management of these patients remains unknown.
Methods: The International Subarachnoid Aneurysm Trial-2 was a randomized trial comparing surgical versus EVT of RIAs considered for surgical clipping, despite the results of previous RCTs, and also eligible for EVT. The primary endpoint was death or dependency according to the modified Rankin Scale score (mRS score > 2) at 1 year.
J Neurosurg
January 2025
19Division of Medical Statistics, Division of Data Science, Foundation for Biomedical Research and Innovation at Kobe; and.
Objective: Studies have demonstrated the effectiveness of hydrogel-coated coils (HGCs) to achieve the composite endpoint of decreased recanalization rates and greater safety. Herein, the authors aimed to assess the true ability of second-generation HGCs to prevent recanalization.
Methods: This randomized controlled study, the HYBRID (Hydrocoil Versus Bare Platinum Coil in Recanalization Imaging Data) trial, comparing HGCs with bare platinum coils (BPCs), was conducted in 43 Japanese institutions.
Neurosurg Rev
January 2025
Department of Neurosurgery, Carl Von Ossietzky University Oldenburg, Oldenburg, Germany.
This study aimed to provide an updated evidence of superior hypophyseal artery (SHA) aneurysms management, including their clinical implications, predictive factors for rupture, therapeutic approaches, and post-treatment outcomes. This systematic review and meta-analysis, following PRISMA guidelines, assessed the literature on superior hypophyseal artery aneurysms. Studies were selected based on predefined criteria, focusing on coiling and clipping interventions.
View Article and Find Full Text PDFClin Neuroradiol
January 2025
Department of Radiology, Kangdong Seong-Sim Hospital, Hallym University College of Medicine, 150, Seongan-ro Gangdong-Gu, Seoul, Korea (Republic of).
Purpose: To compare the diagnostic accuracy of CT angiography (CTA), MR angiography (MRA), and their combined use for detecting unruptured intracranial aneurysms (UIAs).
Methods: Between September 2019 and August 2023, 235 patients suspected of having UIA underwent CTA, MRA, and digital subtraction angiography (DSA)/3-dimensional rotational angiography (3DRA). Two neuroradiologists retrospectively reviewed these images for UIA presence.
BMJ Open
January 2025
Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, Netherlands
Objectives: Aneurysmal subarachnoid haemorrhage (ASAH) is a severe stroke type, preventable by screening for intracranial aneurysms followed by treatment in high-risk individuals. We aimed to develop and validate a risk prediction model for ASAH in the general population to identify high-risk individuals.
Design: We used the population-based prospective cohort studies of the United Kingdom (UK) Biobank for model development and the Trøndelag Health (HUNT) Study for model validation.
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