The novel alpha-amino acid BpAib, a partially conformationally restricted analogue of the currently extensively used 3-(4-benzoylphenyl)alanine (Bpa) photoaffinity label, was synthesized, optically resolved, fully characterized, and appropriately derivatized. An intermolecular photocrosslinking experiment highlighted its regioselective reactivity towards the S-methyl side-chain group of a Met-based dipeptide, which is closely comparable to that of Bpa.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c003943h | DOI Listing |
Publication Analysis
Top Keywords
alpha-amino acid
8
tool photoaffinity
4
photoaffinity labeling
4
labeling studies
4
studies partially
4
partially constrained
4
constrained benzophenone
4
benzophenone based
4
based alpha-amino
4
acid novel
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!