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Drug-Coated Balloon-Based Treatment of Left Main True Bifurcation Lesion.
Catheter Cardiovasc Interv
January 2025
Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam-gu, South Korea.
Background: There is a paucity of data regarding drug-coated balloon (DCB) treatment in the context of left main (LM) true bifurcation lesions.
Aims: The aim of this study was to evaluate the safety and efficacy of DCB-based treatment for unprotected LM true bifurcation lesions.
Methods: A total of 39 patients with LM true bifurcation lesion (Medina: 1,1,1/0,1,1/1,0,1) who were successfully treated with DCB alone or in combination with drug-eluting stent (DES) were retrospectively enrolled into the DCB-based group.
Synergistic antibacterial drug elution from UHMWPE for load-bearing implants.
J Mater Chem B
January 2025
Harris Orthopaedic Laboratory, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
Total joint replacement is a successful procedure for restoring the patient's musculoskeletal mobility and quality of life, but it carries the risk of severe peri-prosthetic joint infections (PJI) and is accompanied by post-operative pain. Cocktails of multiple drugs are often used for prevention/treatment of PJI and for addressing pain. Local drug delivery systems are promising for improving the outcome of the treatment and decreasing the side effects of systemic drugs.
View Article and Find Full Text PDFHow Can We Optimize the Results of Coronary Bioresorbable Scaffolds?
Circ Cardiovasc Interv
January 2025
Department of Cardiology, Hospital Universitario de La Princesa, Madrid, Spain.
Optimal Predilatation Treatment Before Implantation of a Magmaris Bioresorbable Scaffold in Coronary Artery Stenosis: The OPTIMIS Trial.
Circ Cardiovasc Interv
January 2025
Department of Cardiology, Odense University Hospital, Denmark (K.N.H., J.T., M.N., M.H., J.E.-G., K.T.V., A.J., H.S.H., J.F.L., L.O.J.).
Background: Bioresorbable scaffolds (BRS) were developed to overcome limitations related to late stent failures of drug-eluting stents, but lumen reductions over time after implantation of BRS have been reported. This study aimed to investigate if lesion preparation with a scoring balloon compared with a standard noncompliant balloon minimizes lumen reduction after implantation of a Magmaris BRS assessed with optical coherence tomography and intravascular ultrasound.
Methods: Eighty-two patients with stable angina were randomized in a ratio of 1:1 to lesion preparation with a scoring balloon versus a standard noncompliant balloon before implantation of a Magmaris BRS.
Thin film microextraction of PAHs from wastewater samples using an oxine modified iron mesh followed by dispersive liquid-liquid microextraction prior to gas chromatography analysis.
Anal Methods
January 2025
Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran.
In the present research, an attempt has been made to develop a new thin film microextraction method for the extraction of several polycyclic aromatic hydrocarbons from aqueous samples collected from different industrial units prior to their analysis by gas chromatography combined with a flame ionization detector. In this approach, a thin iron mesh was modified by the formation of iron(II) oxinate on its surface and used for the extraction of analytes without an additional sorbent. For this purpose, first, the mesh was immersed in a sulfuric acid solution and then transferred into an 8-hydroxy quinoline (oxine) solution dissolved in ammonia solution.
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