In vitro activity of azithromycin against nontyphoidal Salmonella enterica.

Antimicrob Agents Chemother

Antimicrobial Resistance Unit, Department of Infectious Disease Surveillance and Control, National Institute for Health and Welfare, Helsinki, Finland.

Published: August 2010

The in vitro activity of azithromycin against 1,237 nontyphoidal Salmonella enterica isolates collected from Finnish patients between 2003 and 2008 was investigated. Only 24 (1.9%) of the isolates tested and 15 (5.1%) of the 294 isolates with reduced fluoroquinolone susceptibility had azithromycin MICs of >or=32 microg/ml. These data show that azithromycin has good in vitro activity against nontyphoidal S. enterica, and thus, it may be a good candidate for clinical treatment studies of salmonellosis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916314PMC
http://dx.doi.org/10.1128/AAC.01678-09DOI Listing

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