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Beyond The Basics: Unveiling Superior Vena Cava Compression in Hodgkin's Lymphoma.
Cureus
November 2024
Internal Medicine/Pulmonary Critical Care, Appalachian Regional Healthcare, Harlan, USA.
Hodgkin's lymphoma (HL) is a malignancy of the lymphocytes in the lymph nodes and presents with non-specific systemic symptoms like fever, night sweats, and weight loss. While HL often involves the mediastinum, it rarely causes superior vena cava (SVC) syndrome, and eosinophilia is noted in approximately 15% of cases. Here, we report a unique presentation of HL in a 52-year-old male with a history of chronic pruritus, chronic kidney disease, and inactive hepatitis B.
View Article and Find Full Text PDFA 10-year Review of Severe Eosinophilia and Hypereosinophilia from a Pediatric Hospital in the U.S.
Ann Allergy Asthma Immunol
December 2024
Department of Pediatrics, Division of Allergy and Pulmonary Medicine, Washington University School of Medicine, Saint Louis, MO; Department of Pediatrics, Division of Rheumatology/Immunology, Washington University School of Medicine, Saint Louis, MO. Electronic address:
New Frontiers in Asthma Chest Imaging.
J Allergy Clin Immunol
December 2024
Pulmonary, Critical Care, and Sleep Medicine, University of Kansas Medical Center. Electronic address:
Modern pulmonary imaging can reveal underlying pathological and pathophysiological changes in the lungs of people with asthma, with important clinical implications. A multitude of imaging modalities are now used to examine underlying structure/function relationships including computed tomography, magnetic resonance imaging, optical coherence tomography, and endobronchial ultrasound. Imaging-based biomarkers from these techniques, including airway dimensions, blood vessel volumes, mucus scores, ventilation defect extent and air trapping extent, often have increased sensitivity compared to traditional lung function measurements, and are increasingly used as endpoints in clinical trials.
View Article and Find Full Text PDFA gut commensal protozoan determines respiratory disease outcomes by shaping pulmonary immunity.
Cell
December 2024
Department of Immunology, University of Toronto, Toronto, ON, Canada. Electronic address:
The underlying mechanisms used by the intestinal microbiota to shape disease outcomes of the host are poorly understood. Here, we show that the gut commensal protozoan, Tritrichomonas musculis (T.mu), remotely shapes the lung immune landscape to facilitate perivascular shielding of the airways by eosinophils.
View Article and Find Full Text PDFIntracerebral Hemorrhage with Churg Strauss-Syndrome: Multidisciplinary Collaboration and Literature Review.
Vasc Health Risk Manag
December 2024
Inner Mongolia Medical University Ordos School of Clinical Medicine, Ordos, 017000, People's Republic of China.
Objective: To explore the clinical characteristics and treatment outcomes of intracerebral hemorrhage in eosinophilic granulomatosis with polyangiitis (EGPA).
Methods And Patient Presentation: We report an 18-year-old student of EGPA complicated with intracerebral hemorrhage. The laboratory tests showed a continuous increase in eosinophils.
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