AI Article Synopsis
- Researchers developed new types of copolymeric polyoxoesters using branched-chain methylenethiol functions through lipase-catalyzed polyesterification and polytransesterification processes.
- The reaction involved 1,12-dodecanedioic acid or diethyl 1,12-dodecanedioate, and 1-thioglycerol, using an immobilized lipase B from Candida antarctica, and took between 360 to 480 hours to complete.
- Analysis of the final products revealed that one polyoxoester had a higher molecular weight of approximately 170,000 Da compared to 7,100 Da for the other, and various analytical techniques such as GPC/SEC and NMR were used to characterize them
Article Abstract
Copolymeric polyoxoesters containing branched-chain methylenethiol functions, i.e., poly(1,12-dodecanedioic acid-co-1-thioglycerol) and poly(diethyl 1,12-dodecanedioate-co-1-thioglycerol), were formed by lipase-catalyzed polyesterification and polytransesterification of 1,12-dodecanedioic acid and diethyl 1,12-dodecanedioate, respectively, with 1-thioglycerol (3-mercaptopropane-1,2-diol) using immobilized lipase B from Candida antarctica (Novozym 435) in vacuo without drying agent in the reaction mixture. After 360-480 h, both polyoxoesters were purified by extraction from the reaction mixtures followed by solvent fractionation. The precipitate of poly(1,12-dodecanedioic acid-co-1-thioglycerol) demonstrated a M(W) of ~170,000 Da, whereas a M(W) of ~7,100 Da only was found for poly(diethyl 1,12-dodecanedioate-co-1-thioglycerol). Both polycondensates were analyzed by GPC/SEC, alkali-catalyzed transmethylation, NMR- and FTIR-spectrometry.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10529-010-0311-z | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!