The authors present a treatment procedure in giant-cell tumours of limbs applied in the recent three years at Ist Orthopaedic Clinic in Bratislava. The procedure begins with cytologic verification (in most cases within one stage procedure by peroperative cytologic examination) followed by careful curretage of the lesion, irrigation by liquid non-diluted solution of phenol, irrigation with pure 96% ethylalcohol, irrigation with physiological solution, filling with bone cement. In the methodological part of the contribution the authors discuss toxicity of phenol and risks of this treatment which they confront with the existing data in the literature. Key words: giant-cell tumours, chemoproteolysis, phenol, bone cement.
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