Objective: Various bleaching modalities are now offered to patients, either monitored by the dental office or self-directed, for which relative efficiency is unknown. The aim of this in vitro study was to evaluate the ability of bleaching products and protocols to lighten enamel and dentin.
Method And Materials: Bovine tooth specimens of standardized thickness (2.5 +/- 0.025 mm with similar dentin and enamel thickness) were prepared and stained with whole blood and hemolysate before being submitted to seven supervised or self-directed bleaching regimens: tray-based bleaching using 10% (Opalescence, Ultradent; Nite White, Discus Dental) or light-activated 30% (Metatray, Metatray) carbamide peroxide (CP); 6% (Zoom, Discus Dental) or 9% (TresWhite, Ultradent) hydrogen peroxide (HP); strips (Whitening Strips, Oral B-Rembrandt); and paint-on gel (Paint on Plus, Ivoclar Vivadent) containing 8.1% and 6% HP, respectively. Colorimetric measurements were performed on each specimen side, according to the CIE L*a*b* system, before and after staining, as well as after 5, 10, and the recommended number of bleaching applications.
Results: Color change after recommended number of applications (DEr) varied from 15.72 (Metatray) to 29.67 (Nite White) at enamel and 14.91 (Paint on Plus) to 41.43 (Nite White) at dentin side; Nite White (10% CP) and TresWhite (9% HP) were more effective than Metatray (30% CP) and Paint on Plus (6% HP) after 5 or the recommended number of applications.
Conclusion: In this in vitro study based on bovine teeth, tray-based systems produced the faster and better bleaching effect, regardless of the product and concentration used, at both enamel and dentin sides.
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Mutat Res Genet Toxicol Environ Mutagen
October 2020
European Commission Joint Research Centre, Ispra, Italy.
Mutat Res Genet Toxicol Environ Mutagen
October 2020
European Commission Joint Research Centre, Ispra, Italy.
The bacterial reverse mutation test (Ames test) is the most commonly used genotoxicity test; it is a primary component of the chemical safety assessment data required by regulatory agencies worldwide. Within the current accepted in vitro genotoxicity test battery, it is considered capable of revealing DNA reactivity, and identifying substances that can produce gene mutations via different mechanisms. The previously published consolidated EURL ECVAM Genotoxicity and Carcinogenicity Database, which includes substances that elicited a positive response in the Ames test, constitutes a collection of data that serves as a reference for a number of regulatory activities in the area of genotoxicity testing.
View Article and Find Full Text PDFPLoS Biol
August 2014
DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany.
Microbes hold the key to life. They hold the secrets to our past (as the descendants of the earliest forms of life) and the prospects for our future (as we mine their genes for solutions to some of the planet's most pressing problems, from global warming to antibiotic resistance). However, the piecemeal approach that has defined efforts to study microbial genetic diversity for over 20 years and in over 30,000 genome projects risks squandering that promise.
View Article and Find Full Text PDFObjective: To evaluate in vitro the effects of tooth whitening using gel with Amorphous Calcium Phosphate (ACP) on the bond strength of metal brackets.
Methods: Thirty-six bovine incisors were sectioned at the crown-root interface, and the crowns were then placed in PVC cylinders. The specimens were divided into 3 groups (n = 12) according to whitening treatment and type of gel used, as follows: G1 (control) - no whitening; G2 - whitening with gel not containing ACP (Whiteness Perfect - FGM), G3 - whitening with gel containing ACP (Nite White ACP - Discus Dental).
Int J Dent
July 2011
Oral and Dental Research Institute, Faculty of Dentistry, University of the Western Cape, Private Bag X1, Tygerberg 7505, Cape Town, South Africa.
The purpose of this study was to evaluate the efficacy of two different 10% carbamide peroxide bleaching products just after treatment and after a 6-month follow-up period. Methods. Two 10% carbamide peroxide products (Opalescence PF and Nite White ACP) were applied nightly for 14 days, according to the manufacturers' instructions.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!